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Case Reports
. 2022 Dec 20;10(12):e6756.
doi: 10.1002/ccr3.6756. eCollection 2022 Dec.

Podocyte infolding glomerulopathy after 25 years of clinical remission of lupus nephritis in a patient with systemic lupus erythematosus: A case report and review of literature

Affiliations
Case Reports

Podocyte infolding glomerulopathy after 25 years of clinical remission of lupus nephritis in a patient with systemic lupus erythematosus: A case report and review of literature

Mohamad Hijazi et al. Clin Case Rep. .

Abstract

Podocyte infolding glomerulopathy (PIG) is a rare pathological finding that has gained more recognition recently. Most of the reported cases have been associated with connective tissue diseases especially systemic lupus erythematosus (SLE). Here we report the first case of Infolding Glomerulopathy associated with SLE in the Middle East.

Keywords: lupus nephritis; podocyte infolding glomerulopathy; systemic lupus erythematosus.

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Conflict of interest statement

The authors have no conflict of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Podocyte infolding glomerulopathy. Light microscopic examination of kidney biopsy shows no definite evidence of lupus nephritis. Only mild and focal mesangial expansion was seen.
FIGURE 2
FIGURE 2
(A) Electron micrograph revealing a glomerular capillary with irregularly thickened basement membrane with embedded deposits composed of cytoplasmic extensions from the foot processes. In addition, there is diffuse effacement of the foot processes. (B) Higher magnification electron micrograph featuring thickened basement membrane and embedded aggregates of spherical structures derived from the foot processes.

References

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