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. 2022 Dec 9;14(12):865.
doi: 10.3390/toxins14120865.

Body Composition of Healthy Cats and Cats with Chronic Kidney Disease Fed on a Dry Diet Low in Phosphorus with Maintenance Protein

Daniela P Machado  1   2 , Bruna Ruberti  1 , Fabio A Teixeira  1 , Thiago H A Vendramini  1 , Karina Pfrimer  3 , Fernanda C Chacar  1 , Julio C C Balieiro  1 , Cristiana F F Pontieri  2 , Marcio A Brunetto  1
Affiliations

Body Composition of Healthy Cats and Cats with Chronic Kidney Disease Fed on a Dry Diet Low in Phosphorus with Maintenance Protein

Daniela P Machado et al. Toxins (Basel). .

Abstract

The aim was to evaluate the effect of feeding a low-phosphorus and maintenance protein diet in healthy cats and cats with chronic kidney disease (CKD) with IRIS stages 1 (CKD-1) and 2 (CKD-2). Cats were initially fed a senior diet (30 days) followed by the renal diet (60 days). Body composition, body weight (BW), muscle mass score (MMS), and body condition score (BCS) were assessed before (T30) and after renal diet intake (T60). General mixed linear models were used to assess the effects of fixed groups and moments (T30 × T60), as well as their interaction, in addition to the random effects of animals within each group. Unlike healthy cats and cats with CKD-1, cats with CKD-2 had a loss of BW, lower BCS (p < 0.005), and lower MMS (p = 0.0008) after 60 days of consuming the renal diet. The fat mass and lean body mass (LBM), determined by the deuterium isotopes method, did not change in all cats between T0 and T60. In healthy cats and cats with CKD-1, the renal diet resulted in maintenance of BW, BCS and MMS; but cats with CKD-2 presented lower BCS and did not reduce phosphatemia after consumption.

Keywords: azotemia; body condition score; feline; lean mass.

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Conflict of interest statement

The authors declare no conflict of interest. C.F.F.P. and D.P.M. are current staff of PremieRpet®.

Figures

Figure 1
Figure 1
Flowchart indicating the enrollment, follow-up and analysis of the control group and CKD cats eating the renal diet.
See this image and copyright information in PMC

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