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. 2022 Nov;28(6):597-602.
doi: 10.5152/dir.2022.201044.

Endovascular management of renal angiomyolipomas: Do coils have a benefit in terms of clinical success rates?

Javid Ahmadov  1 , Ferdi Çay  1 , Gonca Eldem  1 , Bülent Akdoğan  2 , Cenk Yücel Bilen  2 , Fazıl Tuncay Aki  2 , Barbaros Erhan Çil  3 , Ali Ergen  2 , Bora Peynircioğlu  3
Affiliations

Endovascular management of renal angiomyolipomas: Do coils have a benefit in terms of clinical success rates?

Javid Ahmadov et al. Diagn Interv Radiol. 2022 Nov.

Abstract

PURPOSE This study evaluated single center results of endovascular treatment in renal angiomyolipoma (AML) to determine whether there is clinical relevance of adding proximal coil embolization to distal particle embolization in terms of safety, efficacy and retreatment rates. METHODS A retrospective analysis was performed to evaluate patients undergoing transarterial embolization for renal AMLs from January 2007 to October 2020. Parameters regarding patient and tumor characteristics, embolization technique, treatment outcome and complications were recorded. Patients were divided into two groups as A (only particle group) and B (particle + coil group) based on the type of embolic agent used for treatment. Comparative analysis was performed between the two groups in terms of tumor size reduction, retreatment and complication rates. RESULT Forty-two patients (37 (88.1%) female, 5 (11.9%) male) harboring 48 AMLs were included in the study. The mean age was 43.46 (range 20 to 78). The technical success rate was 95.8% (46 of 48 procedures). The mean size reduction was 1.94±1 cm (p < 0.001) after treatments however, no significant difference was seen between groups in terms of tumor size reduction. Retreatment rates were 3.1% (1 of 32 cases) in group A and 14.3% (2 of 14 cases) in group B (p = 0.21). No significant difference was found between groups in terms of bleeding and complication rates during the perioperative period. Mean follow-up duration was 26.48±25.71 (range from 2 to 102) months. CONCLUSION In this study, no clear supplementary benefit was observed in terms of safety, and efficacy with the adjunction of coils to distal particle embolization in the management of AMLs.

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Conflict of interest statement

Conflict of interest disclosure The authors declared no conflict of interest.

Figures

Figure 1.
Figure 1.
(a) Selective right renal angiography image obtained from main renal artery shows the AML stain with intratumoral microaneurysms at the mid-lower portion of the kidney. (b) Super selective image obtained from the tumoral feeder depicts tumoral stain and intratumoral microaneurysms more clearly. (c) Angiogram obtained after TAE with microparticles + coil shows the absence of the tumoral stain and intratumoral microaneurysms. AML, angiomyolipoma; TAE, transarterial embolization.
Figure 2.
Figure 2.
Change of pre- and posttreatment tumor sizes in group A and group B. Tumor size reduction was not significant between groups (P  = .32).
See this image and copyright information in PMC

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