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Review
. 2022 Dec 2;12(12):1807.
doi: 10.3390/biom12121807.

Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities

Claudio Frezza  1 , Daniela De Vita  1 , Chiara Toniolo  1 , Fabio Sciubba  1   2 , Lamberto Tomassini  1 , Alessandro Venditti  3 , Armandodoriano Bianco  3 , Mauro Serafini  1 , Sebastiano Foddai  1
Affiliations
Review

Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities

Claudio Frezza et al. Biomolecules. .

Abstract

In this review paper, the occurrence in the plant kingdom, the chemophenetic value and the biological activities associated with two specific phenyl-ethanoid glycosides, i.e., leucosceptoside A and leucosceptoside B, were reported. This is the first work ever conducted on such a subject. Analysis of the literature data clearly led to three important conclusions: leucosceptoside A is much more common in plants than leucosceptoside B; leucosceptoside A exerts more biological activities than leucosceptoside B even if nothing can be generally concluded about which one is actually the most potent; neither of these compounds can be used as a chemophenetic marker. These three aspects and more are discussed in more depth in this work.

Keywords: biological activities; chemophenetics; leucosceptoside A; leucosceptoside B; occurrence in plants.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Structures of leucosceptoside A and leucosceptoside B.
See this image and copyright information in PMC

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