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Editorial
. 2022 Nov 28;10(12):3053.
doi: 10.3390/biomedicines10123053.

Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis

Affiliations
Editorial

Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis

Michal Tomcik. Biomedicines. .

Abstract

Systemic sclerosis (scleroderma, SSc) is one of the most challenging rheumatic diseases, characterized by vasculopathy, dysregulation of the immune response, and progressive tissue fibrosis affecting the skin, lungs, heart, digestive tract, and kidneys [...].

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Conflict of interest statement

The author declares no conflict of interest.

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References

    1. Denton C.P., Khanna D. Systemic sclerosis. Lancet. 2017;390:1685–1699. doi: 10.1016/S0140-6736(17)30933-9. - DOI - PubMed
    1. Papadimitriou T.I., van Caam A., van der Kraan P.M., Thurlings R.M. Therapeutic Options for Systemic Sclerosis: Current and Future Perspectives in Tackling Immune-Mediated Fibrosis. Biomedicines. 2022;10:316. doi: 10.3390/biomedicines10020316. - DOI - PMC - PubMed
    1. Cardoneanu A., Burlui A.M., Macovei L.A., Bratoiu I., Richter P., Rezus E. Targeting Systemic Sclerosis from Pathogenic Mechanisms to Clinical Manifestations: Why IL-6? Biomedicines. 2022;10:318. doi: 10.3390/biomedicines10020318. - DOI - PMC - PubMed
    1. Szabo I., Muntean L., Crisan T., Rednic V., Sirbe C., Rednic S. Novel Concepts in Systemic Sclerosis Pathogenesis: Role for miRNAs. Biomedicines. 2021;9:1471. doi: 10.3390/biomedicines9101471. - DOI - PMC - PubMed
    1. Zaaroor Levy M., Rabinowicz N., Yamila Kohon M., Shalom A., Berl A., Hornik-Lurie T., Drucker L., Tartakover Matalon S., Levy Y. MiRNAs in Systemic Sclerosis Patients with Pulmonary Arterial Hypertension: Markers and Effectors. Biomedicines. 2022;10:629. doi: 10.3390/biomedicines10030629. - DOI - PMC - PubMed

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