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Review
. 2022 Dec 16;13(12):2388.
doi: 10.3390/genes13122388.

Genetic and Epigenetic Etiology of Inflammatory Bowel Disease: An Update

Sara Jarmakiewicz-Czaja  1 , Magdalena Zielińska  1 , Aneta Sokal  1 , Rafał Filip  2   3
Affiliations
Review

Genetic and Epigenetic Etiology of Inflammatory Bowel Disease: An Update

Sara Jarmakiewicz-Czaja et al. Genes (Basel). .

Abstract

Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and remission of the disease. The etiology of IBD is not fully understood. Many studies point to the presence of genetic, immunological, environmental, and microbiological factors and the interactions between them in the occurrence of IBD. The review looks at genetic factors in the context of both IBD predisposition and pharmacogenetics.

Keywords: Crohn’s disease; genetic factors; inflammation bowel disease; pharmacogenetics; ulcerative colitis.

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Conflict of interest statement

The authors declare no conflict of interest.

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