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Review
. 2022 Dec 13;11(24):7389.
doi: 10.3390/jcm11247389.

Effects of Low-Load Blood Flow Restriction Resistance Training on Muscle Strength and Hypertrophy Compared with Traditional Resistance Training in Healthy Adults Older Than 60 Years: Systematic Review and Meta-Analysis

Raúl Fabero-Garrido  1 , Miguel Gragera-Vela  1 , Tamara Del Corral  2 , Juan Izquierdo-García  1   3 , Gustavo Plaza-Manzano  2 , Ibai López-de-Uralde-Villanueva  2
Affiliations
Review

Effects of Low-Load Blood Flow Restriction Resistance Training on Muscle Strength and Hypertrophy Compared with Traditional Resistance Training in Healthy Adults Older Than 60 Years: Systematic Review and Meta-Analysis

Raúl Fabero-Garrido et al. J Clin Med. .

Abstract

Background: There is clinical interest in determining the effects of low-load blood flow restriction (LL-BFR) resistance training on muscle strength and hypertrophy compared with traditional high- and low-load (HL and LL) resistance training in healthy older adults and the influence of LL-BFR training cuff-pressure on these outcomes.

Methods: A search was performed on the MEDLINE, PEDro, CINHAL, Web of Science, Science Direct, Scopus, and CENTRAL databases.

Results: The analysis included 14 studies. HL resistance training produces a small increase in muscle strength (eight studies; SMD, -0.23 [-0.41; -0.05]) but not in muscle hypertrophy (six studies; (SMD, 0.08 [-0.22; 0.38]) when compared with LL-BFR resistance training. Compared with traditional LL resistance training, LL-BFR resistance training produces small-moderate increases in muscle strength (seven studies; SMD, 0.44 [0.28; 0.60]) and hypertrophy (two studies; SMD, 0.51 [0.06; 0.96]). There were greater improvements in muscle strength when higher cuff pressures were applied versus traditional LL resistance training but not versus HL resistance training.

Conclusions: LL-BFR resistance training results in lower muscle strength gains than HL resistance training and greater than traditional LL resistance training in healthy adults older than 60 years. LL-BFR resistance training promotes a similar muscle hypertrophy to HL resistance training but is greater than that of traditional LL resistance training. Applying cuff pressures above the limb occlusion pressure could enhance the increases in muscle strength compared with traditional LL resistance training.

Keywords: aged; blood flow restriction therapy; healthy people programs; human physical conditioning; musculoskeletal physiological phenomena; review.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
PRISMA flow diagram.
Figure 2
Figure 2
Synthesis forest plot for muscle strength and hypertrophy for low-load blood flow restriction training versus high-load resistance training [28,50,51,52,53,54,55,56].
Figure 3
Figure 3
Synthesis forest plot for muscle strength and hypertrophy for low-load blood flow restriction training versus traditional low-load resistance training [28,57,58,59,60,61,62].
See this image and copyright information in PMC

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