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Review
. 2022 Nov 23;10(12):2318.
doi: 10.3390/microorganisms10122318.

Versatile Applications of Cyanobacteria in Biotechnology

Ewa Żymańczyk-Duda  1 , Sunday Ocholi Samson  1 , Małgorzata Brzezińska-Rodak  1 , Magdalena Klimek-Ochab  1
Affiliations
Review

Versatile Applications of Cyanobacteria in Biotechnology

Ewa Żymańczyk-Duda et al. Microorganisms. .

Abstract

Cyanobacteria are blue-green Gram-negative and photosynthetic bacteria which are seen as one of the most morphologically numerous groups of prokaryotes. Because of their ability to fix gaseous nitrogen and carbon dioxide to organic materials, they are known to play important roles in the universal nutrient cycle. Cyanobacteria has emerged as one of the promising resources to combat the issues of global warming, disease outbreaks, nutrition insecurity, energy crises as well as persistent daily human population increases. Cyanobacteria possess significant levels of macro and micronutrient substances which facilitate the versatile popularity to be utilized as human food and protein supplements in many countries such as Asia. Cyanobacteria has been employed as a complementary dietary constituent of feed for poultry and as vitamin and protein supplement in aquatic lives. They are effectively used to deal with numerous tasks in various fields of biotechnology, such as agricultural (including aquaculture), industrial (food and dairy products), environmental (pollution control), biofuel (bioenergy) and pharmaceutical biotechnology (such as antimicrobial, anti-inflammatory, immunosuppressant, anticoagulant and antitumor); recently, the growing interest of applying them as biocatalysts has been observed as well. Cyanobacteria are known to generate a numerous variety of bioactive compounds. However, the versatile potential applications of cyanobacteria in biotechnology could be their significant growth rate and survival in severe environmental conditions due to their distinct and unique metabolic pathways as well as active defensive mechanisms. In this review, we elaborated on the versatile cyanobacteria applications in different areas of biotechnology. We also emphasized the factors that could impede the implementation to cyanobacteria applications in biotechnology and the execution of strategies to enhance their effective applications.

Keywords: bioactive compounds; bioremediation; cyanobacteria; photobiocatalysis.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Scheme 1
Scheme 1
Possible reduction of cinnamaldehyde.
Scheme 2
Scheme 2
Possible effects of light on enzyme activity in phototrophic organisms.
Scheme 3
Scheme 3
Photodecarboxylase action.
Scheme 4
Scheme 4
Cascade of the reactions.
See this image and copyright information in PMC

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References

    1. Huisman J., Codd G.A., Paerl H.W., Ibelings B.W., Verspagen J.M.H., Visser P.M. Cyanobacterial Blooms. Nat. Rev. Microbiol. 2018;16:471–483. doi: 10.1038/s41579-018-0040-1. - DOI - PubMed
    1. Stomp M., Huisman J., Vörös L., Pick F.R., Laamanen M., Haverkamp T., Stal L.J. Colourful Coexistence of Red and Green Picocyanobacteria in Lakes and Seas. Ecol. Lett. 2007;10:290–298. doi: 10.1111/j.1461-0248.2007.01026.x. - DOI - PubMed
    1. Whitton B.A., Potts M. Introduction to the Cyanobacteria. In: Whitton B.A., editor. Ecology of Cyanobacteria II: Their Diversity in Space and Time. Springer; Dordrecht, The Netherlands: Heidelberg, Germany: New York, NY, USA: London, UK: 2012. pp. 1–13.
    1. Rasmussen B., Fletcher I.R., Brocks J.J., Kilburn M.R. Reassessing the First Appearance of Eukaryotes and Cyanobacteria. Nature. 2008;455:1101–1104. doi: 10.1038/nature07381. - DOI - PubMed
    1. Catherine Q., Susanna W., Isidora E.S., Mark H., Aurélie V., Jean-François H. A Review of Current Knowledge on Toxic Benthic Freshwater Cyanobacteria--Ecology, Toxin Production and Risk Management. Water Res. 2013;47:5464–5479. doi: 10.1016/j.watres.2013.06.042. - DOI - PubMed

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