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Review
. 2022 Dec 7;27(24):8641.
doi: 10.3390/molecules27248641.

Bovine Colostrum Treatment of Specific Cancer Types: Current Evidence and Future Opportunities

Ahmad R Alsayed  1 , Luai Z Hasoun  1 , Heba A Khader  2 , Iman A Basheti  1 , Andi Dian Permana  3
Affiliations
Review

Bovine Colostrum Treatment of Specific Cancer Types: Current Evidence and Future Opportunities

Ahmad R Alsayed et al. Molecules. .

Abstract

Worldwide, the incidence of cancer is on the rise. Current cancer treatments include chemotherapy, radiation therapy, and surgery. Chemotherapy and radiation treatment are typically associated with severe adverse effects and a decline in patients' quality of life. Anti-cancer substances derived from plants and animals need to be evaluated therapeutically as it is cost-effective, have fewer side effects, and can improve cancer patients' quality of life. Recently, bovine colostrum (BC) has attracted the interest of numerous researchers investigating its anti-cancer potential in humans. Dressings loaded with BC are beneficial in treating chronic wounds and diabetic foot ulcers. Lactoferrin, a glycoprotein with potent anti-oxidant, anti-inflammatory, anti-cancer, and anti-microbial effects, is abundant in BC. The BC pills successfully promote the regression of low-grade cervical intraepithelial neoplasia when administered intravaginally. The biological, genetic, and molecular mechanisms driving BC remain to be determined. Oral BC supplements are generally well-tolerated, but some flatulence and nausea may happen. To evaluate the therapeutic effects, long-term safety, and appropriate dosages of BC drugs, well-designed clinical trials are necessary. The purpose of this article is to emphasize the anti-cancer potential of BC and its constituents.

Keywords: anti-cancer; bovine colostrum; cancer; chemotherapy; lactoferrin; natural products; treatment.

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Conflict of interest statement

The authors declare no conflict of interest.

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