Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Oct 14;7(3-4):133-137.
doi: 10.1515/iss-2021-0037. eCollection 2022 Dec.

Thyroid liposarcoma: a case report

Affiliations
Case Reports

Thyroid liposarcoma: a case report

Maxime Gerard et al. Innov Surg Sci. .

Abstract

Objectives: Thyroid liposarcoma is a rare tumor. Its low prevalence accounts for the scarcity of data in the literature, which consists mostly of small studies and case reports.

Case presentation: We present the case of a 60 years old male with no past medical or past surgical history and presented with neck discomfort and a large left thyroid nodule. Thyroid ultrasound and CT scan were performed and confirmed the existence of a thyroid nodule most probably inside the left inferior thyroid lobe. In the posterior mediastinum, two fatty formations were found. To complete, an MRI was performed, showing a mixed lesion, of the lower neck and upper chest. The patient underwent an extended resection which consisted of an en bloc resection of the lesion (left thyroid lobectomy and isthmus resection) by an anterior transverse cervical incision and a sternotomy. Tracheal and laryngeal shaving and esophageal shaving with resection of the esophageal muscularis was performed as well. The pathological evaluation of the specimen showed a grade II dedifferentiated liposarcoma with an inflammatory component.

Conclusions: Thyroid liposarcoma is a rare lesion of the thyroid. Its management requires an exhaustive workup followed by an en bloc resection of the lesion. Depending on the histology, postoperative radiation therapy may or may not be necessary.

Keywords: sarcoma; thyroid liposarcoma; thyroid surgery.

PubMed Disclaimer

Conflict of interest statement

Competing interests: Authors state no conflict of interest.

Figures

Figure 1:
Figure 1:
US examination of the thyroid.
Figure 2:
Figure 2:
Second CT scan (with contrast). (A) Coronal view. (B) axial view.
Figure 3:
Figure 3:
MRI of the left cervical lesion (axial view).
Figure 4:
Figure 4:
Pathology specimen: left thyroid lobectomy.

References

    1. Kraus DH, Dubner S, Harrison LB, Strong EW, Hajdu SI, Kher U, et al. Prognostic factors for recurrence and survival in head and neck soft tissue sarcomas. Cancer. 1994;74:697–702. doi: 10.1002/1097-0142(19940715)74:2<697::aid-cncr2820740224>3.0.co;2-a. - DOI - PubMed
    1. Enterline HT, Culberson JD, Rochlin DB, Brady LW. Liposarcoma. A clinical and pathological study of 53 cases. Cancer. 1960;13:932–50. doi: 10.1002/1097-0142(196009/10)13:5<932::aid-cncr2820130512>3.0.co;2-s. - DOI - PubMed
    1. Terrier P. Les liposarcomes. Ann Pathol. 2012;32:S108–10. doi: 10.1016/j.annpat.2012.07.004. - DOI - PubMed
    1. Spielman DB, Badhey A, Kadakia S, Inman JC, Ducic Y. Rare thyroid malignancies: an overview for the oncologist. Clin Oncol. 2017;29:298–306. doi: 10.1016/j.clon.2017.01.041. - DOI - PubMed
    1. The WHO Classification of Tumours of Soft Tissue and Bone (Sarcomas) [Internet] Liddy Shriver Sarcoma Initiative. http://sarcomahelp.org/reviews/who-classification-sarcomas.html [cité 18 avr 2021]. Disponible sur.

Publication types