Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jan;44(1):15-19.
doi: 10.1016/j.tips.2022.10.005. Epub 2022 Dec 8.

Monkeypox: potential vaccine development strategies

Affiliations

Monkeypox: potential vaccine development strategies

José Manuel Lozano et al. Trends Pharmacol Sci. 2023 Jan.

Abstract

A multicountry outbreak of monkeypox has gained global attention. Basic research including structural and immunological investigation on monkeypox virus (MPXV) is central to design effective solutions of treatment with antivirals and appropriate vaccines. We summarize some information about this virus and its re-emergence and the current vaccines that are proposed to limit its spread and present some possible avenues for developing new vaccines.

Keywords: emerging infection; orthopoxvirus; peptides; smallpox; synthetic vaccines.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The authors declare that the research was conducted in the absence of any commercial or financial relationships that could constitute a potential conflict of interest.

References

    1. Kaler J., et al. Monkeypox: a comprehensive review of transmission, pathogenesis, and manifestation. Cureus. 2022;14 - PMC - PubMed
    1. Bunge E.M., et al. The changing epidemiology of human monkeypox—a potential threat? A systematic review. PLoS Negl. Trop. Dis. 2022;16 - PMC - PubMed
    1. Thornhill J.P., et al. Monkeypox virus infection in humans across 16 countries — April–June 2022. N. Engl. J. Med. 2022;387:679–691. - PubMed
    1. Lum F.M., et al. Monkeypox: disease epidemiology, host immunity and clinical interventions. Nat. Rev. Immunol. 2022;22:597–613. - PMC - PubMed
    1. Kmiec D., Kirchhoff F. Monkeypox: a new threat? Int. J. Mol. Sci. 2022;23:7866. - PMC - PubMed

Publication types