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Case Reports
. 2022 Dec 23;15(12):e254189.
doi: 10.1136/bcr-2022-254189.

Olmesartan-associated sprue-like enteropathy

Naoki Aoyama  1 , Tetsuro Inokuma  2 , Yuki Nakanishi  3 , Akihisa Fukuda  3
Affiliations
Case Reports

Olmesartan-associated sprue-like enteropathy

Naoki Aoyama et al. BMJ Case Rep. .
No abstract available

Keywords: Drugs: gastrointestinal system; Endoscopy; Gastrointestinal system; Malabsorption; Unwanted effects / adverse reactions.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Upper gastrointestinal endoscopy reveals multiple granular protrusion in the duodenal bulb (A) and mucosal atrophy from descending to transverse part of the duodenum (B).
Figure 2
Figure 2
Antegrade double-balloon enteroscopy reveals diffuse villous atrophy (A) throughout the duodenum and ileum with patchy reddening and erosions (B).
Figure 3
Figure 3
Capsule endoscopy shows diffuse villous atrophy (A), erosions (B) and patchy reddening (C).
Figure 4
Figure 4
A biopsy from duodenum is performed. H&E staining reveals villous atrophy and disappearance of the crypts (A, B).
Figure 5
Figure 5
Upper gastrointestinal endoscopy (A) and antegrade double-balloon enteroscopy (B) show the largely healed state of mucosal atrophy.
See this image and copyright information in PMC

References

    1. Kamal A, Fain C, Park A, et al. . Angiotensin II receptor blockers and gastrointestinal adverse events of resembling sprue-like enteropathy: a systematic review. Gastroenterol Rep 2019;7:162–7. 10.1093/gastro/goz019 - DOI - PMC - PubMed
    1. Marthey L, Cadiot G, Seksik P, et al. . Olmesartan-associated enteropathy: results of a national survey. Aliment Pharmacol Ther 2014;40:1103–9. 10.1111/apt.12937 - DOI - PubMed

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