Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Feb;29(2):389-392.
doi: 10.3201/eid2902.220712. Epub 2022 Dec 23.

Longitudinal Analysis of Electronic Health Information to Identify Possible COVID-19 Sequelae

Eleanor S Click, Donald Malec, Jennifer Chevinsky, Guoyu Tao, Michael Melgar, Jennifer Giovanni, Adi Gundlapalli, Deblina Datta, Karen K Wong

Longitudinal Analysis of Electronic Health Information to Identify Possible COVID-19 Sequelae

Eleanor S Click et al. Emerg Infect Dis. 2023 Feb.

Abstract

Ongoing symptoms might follow acute COVID-19. Using electronic health information, we compared pre‒ and post‒COVID-19 diagnostic codes to identify symptoms that had higher encounter incidence in the post‒COVID-19 period as sequelae. This method can be used for hypothesis generation and ongoing monitoring of sequelae of COVID-19 and future emerging diseases.

Keywords: COVID-19; SARS-CoV-2; United States; coronavirus disease; coronaviruses; electronic health information sequelae; longitudinal analysis; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

PubMed Disclaimer

References

    1. Al-Aly Z, Xie Y, Bowe B. High-dimensional characterization of post-acute sequelae of COVID-19. Nature. 2021;594:259–64. 10.1038/s41586-021-03553-9 - DOI - PubMed
    1. Datta SD, Talwar A, Lee JT. A proposed framework and timeline of the spectrum of disease due to SARS-CoV-2 infection: illness beyond acute infection and public health implications. JAMA. 2020;324:2251–2. 10.1001/jama.2020.22717 - DOI - PubMed
    1. Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, et al. Post-acute COVID-19 syndrome. Nat Med. 2021;27:601–15. 10.1038/s41591-021-01283-z - DOI - PMC - PubMed
    1. Carfì A, Bernabei R, Landi F, Gemelli Against C-P-ACSG; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA. 2020;324:603–5. 10.1001/jama.2020.12603 - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention. Public health recommendations: evaluating and caring for patients with post-COVID conditions: interim guidance [cited 2022 Aug 22]. https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-care/post-covid-p...