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. 2023 Feb;192(3):e2538.
doi: 10.1002/vetr.2538. Epub 2022 Dec 25.

Differentiating Strongylus vulgaris-associated, non-strangulating intestinal infarctions from idiopathic peritonitis and acute colitis in horses

Lea Poulsen  1 , Frida V Henriksson  1 , Melissa Dahl  1 , Marie Louise Honoré  1 , Susanne N Olsen  1 , Páll S Leifsson  2 , Jacob Staerk-Østergaard  3 , Stine Jacobsen  1 , Tina H Pihl  1
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Differentiating Strongylus vulgaris-associated, non-strangulating intestinal infarctions from idiopathic peritonitis and acute colitis in horses

Lea Poulsen et al. Vet Rec. 2023 Feb.

Abstract

Background: Horses with non-strangulating intestinal infarction (NSII) are often misdiagnosed with idiopathic peritonitis or acute colitis. Early diagnosis is essential to ensure early surgical intervention and improve survival.

Methods: Clinical and laboratory data from horses admitted to the University of Copenhagen Large Animal Teaching Hospital with NSII, idiopathic peritonitis or acute colitis between 2009 and 2018 were used for univariate comparisons and a multivariable logistic regression model for prediction of NSII.

Results: Two hundred and thirty-one horses were included. A multivariable model for the prediction of NSII included gastric reflux (more than 5 L) (odds ratio [OR] 8.7; 95% confidence interval [CI] 2.1-36.2), abnormal findings palpated per rectum (intestinal dilatations/impactions [OR 4.43; 95% CI 1.43-13.38], colon displacements [OR 23.16; 95% CI 5.26-101.97] or intestinal mass [OR 179.7; 95% CI 23.5-1375.5]), white blood cell count (OR 1.2; 95% CI 1.1-1.4), packed cell volume (OR 0.9; 95% CI 0.8-0.9), age (OR 0.9; 95% CI 0.8-1.0) and heart rate (OR 1.1; 95% CI 1.0-1.1). The model had a low false positive rate (5%), but a high false negative rate (50%).

Limitations: Due to the retrospective nature of the study, sample collection was inconsistent, resulting in missing values.

Conclusion: The model had some capability in predicting NSII. However, the high risk of false negatives means that exploratory laparotomy should be considered in horses with peritonitis of unknown aetiology in areas where Strongylus vulgaris is prevalent and occurrence of idiopathic peritonitis is low.

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References

REFERENCES

    1. Duncan JL, Pirie HM. The life cycle of Strongylus vulgaris in the horse. Res Vet Sci. 1972;13(4):374-9.
    1. Duncan JL, Pirie HM. The pathogenesis of single experimental infections with Strongylus vulgaris in foals. Res Vet Sci. 1975;18(1):82-93.
    1. Pihl TH, Nielsen MK, Olsen SN, Leifsson PS, Jacobsen S. Nonstrangulating intestinal infarctions associated with Strongylus vulgaris: clinical presentation and treatment outcomes of 30 horses (2008-2016). Equine Vet J. 2018;50(4):474-80.
    1. Nielsen MK, Jacobsen S, Olsen SN, Bousquet E, Pihl T. Nonstrangulating intestinal infarction associated with Strongylus vulgaris in referred Danish equine cases. Equine Vet J. 2016;48(3):376-9.
    1. Drudge JH. Clinical aspects of Strongylus vulgaris infection in the horse. Emphasis on diagnosis, chemotherapy, and prophylaxis. Vet Clin North Am Large Anim Pract. 1979;1(2):251-65.

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