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. 2022 Dec 9:13:1061686.
doi: 10.3389/fimmu.2022.1061686. eCollection 2022.

Omicron variants of SARS-CoV-2 and long COVID

Chengliang Yang  1   2   3 , Hedi Zhao  4 , Casey P Shannon  1   2 , Scott J Tebbutt  1   2   3
Affiliations

Omicron variants of SARS-CoV-2 and long COVID

Chengliang Yang et al. Front Immunol. .

Abstract

Understanding the epidemiology of long COVID and emerging variants has significant public-health implications as physical interventions and restrictions that help limit viral spread are eased globally. Here, we provide rationales for the necessity of updating current vaccines to improve protection against omicron and emerging variants, as well as more research into understanding the epidemiology and mechanisms of long COVID.

Keywords: COVID-19; SARS-CoV-2; long covid; omicron variant; post COVID-19 condition; vaccine.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Estimated number of people living in the U.K. with long COVID of Omicron origin. LC, long COVID; K, thousand. “Data source: Office for National Statistics. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/previousReleases”.
See this image and copyright information in PMC

References

    1. Huang L, Yao Q, Gu X, Wang Q, Ren L, Wang Y, et al. . 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study. Lancet (2021) 398:747–58. doi: 10.1016/S0140-6736(21)01755-4 - DOI - PMC - PubMed
    1. Yang C, Zhao H, Tebbutt SJ. Long-term effects on survivors with COVID-19. Lancet (2021) 398:1872. doi: 10.1016/S0140-6736(21)02323-0 - DOI - PMC - PubMed
    1. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, et al. . More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Sci Rep (2021) 11:16144. doi: 10.1038/s41598-021-95565-8 - DOI - PMC - PubMed
    1. Global Burden of Disease Long COVID Collaborators. Wulf Hanson S, Abbafati C, Aerts JG, Al-Aly Z, Ashbaugh C, et al. . Estimated global proportions of individuals with persistent fatigue, cognitive, and respiratory symptom clusters following symptomatic COVID-19 in 2020 and 2021. JAMA (2022) 328:1604–15. doi: 10.1001/jama.2022.18931 - DOI - PMC - PubMed
    1. Yang C, Zhao H, Tebbutt SJ. A glimpse into long COVID and symptoms. Lancet Respir Med (2022) 10:e81. doi: 10.1016/S2213-2600(22)00217-X - DOI - PMC - PubMed

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