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Case Reports
. 2022 Dec 14;17(4):635-637.
doi: 10.1055/s-0042-1757627. eCollection 2022 Dec.

Craniocerebral Maduramycosis: Masquerading as a Tumor

Inuganti Venkata Renuka  1 , Chitturi Ramya  1 , Velivela Kiran Chand  2 , Tammina Mohana Sri Vidya  1 , Salumuri Premchand  2
Affiliations
Case Reports

Craniocerebral Maduramycosis: Masquerading as a Tumor

Inuganti Venkata Renuka et al. Asian J Neurosurg. .

Abstract

Eumycetomas of craniocerebral are rare, and we report an extraordinary case of maduramycosis involving brain and skull bone in a middle-aged male who presented with complaints of headache, behavioral abnormalities, and memory disturbances for 3 months. Imaging showed a frontal lesion. It was mistaken for a tumor clinically and radiologically. Craniocerebral eumycetoma usually presents as a mass on the scalp with sinuses. Our case presented as a brain tumor without a soft tissue mass or discharging sinuses. It is essential to keep in mind this mode of presentation, and only a biopsy will aid in diagnosis.

Keywords: craniocerebral; eumycetoma; maduramycosis.

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Conflict of interest statement

Conflict of Interest None declared.

Figures

Fig. 1
Fig. 1
Well-defined mass lesion arising from right frontal bone with significant mass effect of frontal lobe and extensive perilesional edema, possible subdural osteoma from right frontal bone/atypical meningioma. ( A ) T1-weighted, ( B ) T2-weighted, ( C ) T2-weighted fluid-attenuated inversion recovery, and ( D ) T2-weighted sagittal images.
Fig. 2
Fig. 2
Intraoperatively lesion pinkish white, mildly vascular, and infiltrating the surrounding parenchyma.
Fig. 3
Fig. 3
( A and B ) Maduramycosis colonies, with neutrophils, epithelioid cells, plasma cells, and multinucleated giant cells (hematoxylin and eosin, 100× and 400 × ).
Fig. 4
Fig. 4
( A and B ) Special stains periodic acid Schiff stain (PAS) and Grocott-Gomori silver methenamine stain (GMS) positivity in fungal colonies composed of radially arranged, septate filamentous hyphae ( A: PAS, 400 × ; B: GMS, 400 × ).
See this image and copyright information in PMC

References

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