Personality traits are not associated with changes in employment status over 3 years in persons with multiple sclerosis

K van der Hiele¹, Eea van Egmond^{1

2

3

4}, Dam van Gorp², P J Jongen^{5

6}, M F Reneman⁷, Jjl van der Klink^{8

9}, Eac Beenakker¹⁰, Jjj van Eijk¹¹, Stfm Frequin¹², E Hoitsma¹³, Ohh Gerlach¹⁴, J P Mostert¹⁵, Wim Verhagen¹⁶, Map Heerings¹⁷, Ham Middelkoop^{1

18}, L H Visser^{2

4}

Affiliations

¹ Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands.
² Department of Care Ethics, University of Humanistic Studies, Utrecht, The Netherlands.
³ National Multiple Sclerosis Foundation, Rotterdam, The Netherlands.
⁴ Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
⁵ MS4 Research Institute, Nijmegen, The Netherlands.
⁶ Department of Community & Occupational Medicine, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
⁷ Department of Rehabilitation Medicine, Centre for Rehabilitation, University of Groningen, University Medical Centre Groningen, Haren, The Netherlands.
⁸ Department of Social and Behavioural Sciences, Tranzo Scientific Centre for Care and Welfare, Tilburg University, Tilburg, The Netherlands.
⁹ Optentia, North West University of South Africa, Vanderbijlspark, South Africa.
¹⁰ Department of Neurology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands.
¹¹ Department of Neurology, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.
¹² Department of Neurology, St Antonius Hospital, Nieuwegein, The Netherlands.
¹³ Department of Neurology, Alrijne Hospital Leiden, Leiden, The Netherlands.
¹⁴ Department of Neurology, Zuyderland Medical Centre, Sittard-Geleen, The Netherlands.
¹⁵ Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands.
¹⁶ Department of Neurology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
¹⁷ Department of Human Genetics, Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.
¹⁸ Department of Neurology & Neuropsychology, Leiden University Medical Centre, Leiden, The Netherlands.

PMID: 36570872
PMCID: PMC9772955
DOI: 10.1177/20552173221145576

Personality traits are not associated with changes in employment status over 3 years in persons with multiple sclerosis

K van der Hiele et al. Mult Scler J Exp Transl Clin. 2022.

. 2022 Dec 19;8(4):20552173221145576.

doi: 10.1177/20552173221145576. eCollection 2022 Oct-Dec.

Authors

Affiliations

¹ Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands.
² Department of Care Ethics, University of Humanistic Studies, Utrecht, The Netherlands.
³ National Multiple Sclerosis Foundation, Rotterdam, The Netherlands.
⁴ Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
⁵ MS4 Research Institute, Nijmegen, The Netherlands.
⁶ Department of Community & Occupational Medicine, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
⁷ Department of Rehabilitation Medicine, Centre for Rehabilitation, University of Groningen, University Medical Centre Groningen, Haren, The Netherlands.
⁸ Department of Social and Behavioural Sciences, Tranzo Scientific Centre for Care and Welfare, Tilburg University, Tilburg, The Netherlands.
⁹ Optentia, North West University of South Africa, Vanderbijlspark, South Africa.
¹⁰ Department of Neurology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands.
¹¹ Department of Neurology, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.
¹² Department of Neurology, St Antonius Hospital, Nieuwegein, The Netherlands.
¹³ Department of Neurology, Alrijne Hospital Leiden, Leiden, The Netherlands.
¹⁴ Department of Neurology, Zuyderland Medical Centre, Sittard-Geleen, The Netherlands.
¹⁵ Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands.
¹⁶ Department of Neurology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
¹⁷ Department of Human Genetics, Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.
¹⁸ Department of Neurology & Neuropsychology, Leiden University Medical Centre, Leiden, The Netherlands.

PMID: 36570872
PMCID: PMC9772955
DOI: 10.1177/20552173221145576

Abstract

Previous research discovered a protective effect of higher conscientiousness against a 3-year deterioration in employment status in persons with multiple sclerosis (pwMS). To replicate these findings, we used data from a multicentre prospective cohort study where 145 employed pwMS completed questionnaires, neurological and neuropsychological examinations at baseline and after 3 years. A 3-year deterioration in employment status was reported in 31.0%. We observed no differences in personality, demographics or clinical characteristics between pwMS with deteriorated or stable employment status. These null findings may be partly explained by the classification of deteriorated employment status, which does not reflect Dutch labour conditions.

Keywords: Multiple sclerosis; employment status; fatigue; mood; personality; prospective study.

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Conflict of interest statement

The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: PJJ received honoraria from Bayer Netherlands and Orikami Personalized Health Care, the Netherlands, for consultancy activities and is chairman of the MSmonitor foundation, the Netherlands. JJJvE received honoraria for lectures and honoraria for advisory boards from Sanofi Genzyme, Roche, Merck Serono, Novartis. STFMF received honoraria for lectures, grants for research and honoraria for advisory boards from Sanofi Genzyme, Merck Serono, Novartis, Biogen. EH received honoraria for lectures and advisory boards, and grants for research from Bayer, Biogen, Roche, Sanofi Genzyme, Merck Serono, Novartis. WIMV received honoraria for lectures from Biogen and Merck Serono, reimbursement for hospitality from Biogen, Sanofi Genzyme and Merck Serono, and honoraria for advisory boards from Merck Serono. LHV received honoraria for lectures and honoraria for advisory boards from Merck Serono and Novartis.

Figures

**Figure 1.**
Specification of deterioration in employment status at 3-year follow up.

See this image and copyright information in PMC

References

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1. van der Hiele K, van Gorp DAM, van Egmond EEA, et al. Self-reported occupational functioning in persons with relapsing-remitting multiple sclerosis: does personality matter? J Neurol Sci 2021; 427: 117561. - PubMed
1. Jaworski MG, Fuchs TA, Dwyer MG, et al. Conscientiousness and deterioration in employment status in multiple sclerosis over 3 years. Mult Scler 2021; 27: 1125–1135. - PubMed

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Personality traits are not associated with changes in employment status over 3 years in persons with multiple sclerosis

Affiliations

Personality traits are not associated with changes in employment status over 3 years in persons with multiple sclerosis

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

LinkOut - more resources

Full Text Sources