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Editorial
. 2023 May;75(5):661-663.
doi: 10.1002/art.42430. Epub 2023 Feb 24.

The NLRP3 Conundrum

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Editorial

The NLRP3 Conundrum

James T Rosenbaum et al. Arthritis Rheumatol. 2023 May.
No abstract available

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    1. Meng J, Li N, Liu X, et al. NLRP3 attenuates intraocular inflammation by inhibiting AIM2-mediated pyroptosis through the phosphorylated salt-inducible kinase 1/sterol regulatory element binding transcription factor 1 pathway. Arthritis Rheumatol 2023;75:842-55.
    1. Amaral FA, Costa VV, Tavares LD, et al. NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout. Arthritis Rheum 2012;64:474-84.
    1. Renaudin F, Orliaguet L, Castelli F, et al. Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages. Ann Rheum Dis 2020;79:1506-14.
    1. Kim EH, Park MJ, Park S, et al. Increased expression of the NLRP3 inflammasome components in patients with Behcet's disease. J Inflamm (Lond) 2015;12:41.

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