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Review
. 2023 Feb;16(2):39-47.
doi: 10.1007/s12178-022-09814-y. Epub 2022 Dec 28.

The Effect of Diabetes and Metabolic Syndrome on Spine Surgery Outcomes

Affiliations
Review

The Effect of Diabetes and Metabolic Syndrome on Spine Surgery Outcomes

Anitesh Bajaj et al. Curr Rev Musculoskelet Med. 2023 Feb.

Abstract

Purpose of review: Diabetes and metabolic syndrome are highly prevalent in patients undergoing spine surgery. This review aims to capture both the findings of recently published literature investigating the effects of diabetes and metabolic syndrome on spine surgery outcomes and the current best practices in patient management.

Recent findings: Diabetes and metabolic syndrome both contribute to worse outcomes in patients undergoing spine surgery. Although patients with diabetes are at greater risk of complications, those with uncontrolled diabetes experience increased healthcare costs and greater odds of postoperative complications. Furthermore, metabolic syndrome is repeatedly shown to have an adverse effect on spine surgery outcomes, including healthcare costs and medical complications. Spine surgeons should coordinate care with primary care physicians to optimize the preoperative profile of patients with comorbidities like diabetes and metabolic syndrome to minimize operative risk. With the shift to value-based care, understanding the patient factors that lead to complications is becoming increasingly important. Future studies should build upon the current literature and design preoperative interventions for at-risk patients. Additionally, further research is needed to analyze the modulatory effects of the social determinants of health in patients with diabetes and metabolic syndrome.

Keywords: Diabetes; Metabolic syndrome; Spine complications; Spine surgery; Surgical outcomes; Uncontrolled diabetes.

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Conflict of interest statement

Anitesh Bajaj, Rohan M. Shah, Hogan Brecount, Steven Kurapaty, Alpesh A. Patel, and Srikanth N. Divi declare that they have no conflicts of interest.

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References

    1. Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9(th) edition. Diabetes Res Clin Pract. 2019;157:107843. 10.1016/j.diabres.2019.107843. - PubMed
    1. Hirode G, Wong RJ. Trends in the prevalence of metabolic syndrome in the United States, 2011-2016. JAMA. 2020;323(24):2526–2528. doi: 10.1001/jama.2020.4501. - DOI - PMC - PubMed
    1. Aguilar M, Bhuket T, Torres S, Liu B, Wong RJ. Prevalence of the metabolic syndrome in the United States, 2003-2012. JAMA. 2015;313(19):1973–1974. doi: 10.1001/jama.2015.4260. - DOI - PubMed
    1. Laiteerapong N, Huang ES. Diabetes in older adults. In: rd, Cowie CC, Casagrande SS, Menke A, Cissell MA, Eberhardt MS, et al., editors. Diabetes in America. Bethesda (MD) 2018.
    1. Cloyd JM, Acosta FL, Jr, Cloyd C, Ames CP. Effects of age on perioperative complications of extensive multilevel thoracolumbar spinal fusion surgery. J Neurosurg Spine. 2010;12(4):402–408. doi: 10.3171/2009.10.SPINE08741. - DOI - PubMed