Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Dec 29;15(12):e252256.
doi: 10.1136/bcr-2022-252256.

Myocardial infarction after craniotomy for asymptomatic meningioma

Affiliations
Case Reports

Myocardial infarction after craniotomy for asymptomatic meningioma

Kristen Michelle Westfall et al. BMJ Case Rep. .

Abstract

A man in his 40s with a history of coronary artery disease previously treated with a drug-eluting stent presented for elective craniotomy and resection of an asymptomatic but enlarging meningioma. During his craniotomy, he received desmopressin and tranexamic acid for surgical bleeding. Postoperatively, the patient developed chest pain and was found to have an ST-elevation myocardial infarction (MI). Because of the patient's recent neurosurgery, standard post-MI care was contraindicated and he was instead managed symptomatically in the intensive care unit. Echocardiogram on postoperative day 1 demonstrated no regional wall motion abnormalities and an ejection fraction of 60%. His presentation was consistent with thrombosis of his diagonal stent. He was transferred out of the intensive care unit on postoperative day 1 and discharged home on postoperative day 3.

Keywords: Adult intensive care; Drug therapy related to surgery; Ischaemic heart disease; Neurosurgery; Unwanted effects / adverse reactions.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
MRI brain demonstrating left frontal extra-axial mass measuring 2.3 cm × 5.3 cm with moderate local mass effect on left frontal and opercular regions.
Figure 2
Figure 2
ECG with ST elevations in leads I, aVL, V2–V6 and reciprocal change in leads III, aVR, aVF and V1.
Figure 3
Figure 3
Low-power and high-power images of mass resection pathology demonstrating meningothelial meningioma grade 1.

References

    1. Goel NJ, Mallela AN, Agarwal P, et al. . Complications predicting perioperative mortality in patients undergoing elective craniotomy: a population-based study. World Neurosurg 2018;118:e195–205. 10.1016/j.wneu.2018.06.153 - DOI - PubMed
    1. Lee AT, Gagnidze A, Pan SR, et al. . Preoperative low-dose aspirin exposure and outcomes after emergency neurosurgery for traumatic intracranial hemorrhage in elderly patients. Anesth Analg 2017;125:514–20. 10.1213/ANE.0000000000002053 - DOI - PubMed
    1. Li M, Yang S, Liu Q, et al. . Evaluating the safety of early surgery for ruptured intracranial aneurysms in patients with long-term aspirin use: a propensity score matching study. Chin Neurosurg J 2020;6:1–6. 10.1186/s41016-020-00216-y - DOI - PMC - PubMed
    1. Hanalioglu S, Sahin B, Sahin OS, et al. . Effect of perioperative aspirin use on hemorrhagic complications in elective craniotomy for brain tumors: results of a single-center, retrospective cohort study. J Neurosurg 2019;132:1529–38. 10.3171/2018.12.JNS182483 - DOI - PubMed
    1. Rahman M, Donnangelo LL, Neal D, et al. . Effects of perioperative acetyl salicylic acid on clinical outcomes in patients undergoing craniotomy for brain tumor. World Neurosurg 2015;84:41–7. 10.1016/j.wneu.2015.02.016 - DOI - PubMed

Publication types

LinkOut - more resources