Enhancing childhood cancer targetability

Ammar S Naqvi^{1

2

3}, Jo Lynne Rokita^{4

5

6}

Affiliations

¹ Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
² Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
³ Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
⁴ Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA. rokita@email.chop.edu.
⁵ Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA. rokita@email.chop.edu.
⁶ Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA. rokita@email.chop.edu.

Comment

Ammar S Naqvi et al. Nat Cancer. 2023 Feb.

. 2023 Feb;4(2):153-155.

doi: 10.1038/s43018-022-00472-0.

Ammar S Naqvi^{1

2

3}, Jo Lynne Rokita^{4

5

6}

¹ Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
² Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
³ Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
⁴ Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA. rokita@email.chop.edu.
⁵ Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA. rokita@email.chop.edu.
⁶ Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA. rokita@email.chop.edu.

No abstract available

Comment on

The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.
Villani A, Davidson S, Kanwar N, Lo WW, Li Y, Cohen-Gogo S, Fuligni F, Edward LM, Light N, Layeghifard M, Harripaul R, Waldman L, Gallinger B, Comitani F, Brunga L, Hayes R, Anderson ND, Ramani AK, Yuki KE, Blay S, Johnstone B, Inglese C, Hammad R, Goudie C, Shuen A, Wasserman JD, Venier RE, Eliou M, Lorenti M, Ryan CA, Braga M, Gloven-Brown M, Han J, Montero M, Spatare F, Whitlock JA, Scherer SW, Chun K, Somerville MJ, Hawkins C, Abdelhaleem M, Ramaswamy V, Somers GR, Kyriakopoulou L, Hitzler J, Shago M, Morgenstern DA, Tabori U, Meyn S, Irwin MS, Malkin D, Shlien A. Villani A, et al. Nat Cancer. 2023 Feb;4(2):203-221. doi: 10.1038/s43018-022-00474-y. Epub 2022 Dec 30. Nat Cancer. 2023. PMID: 36585449 Free PMC article.

1. American Cancer Society. Key statistics for childhood cancers. https://go.nature.com/3Bc2pQs (accessed 14 September 2022).
1. American Cancer Society. Childhood 5-year survival. https://go.nature.com/3FsrE3I (accessed 14 September 2022).
1. Villani, A. et al. Nat. Cancer https://doi.org/10.1038/s43018-022-00474-y (2022).
1. Alexandrov, L. B. et al. Nature 578, 94–101 (2020). - DOI - PubMed - PMC
1. Aronson, M. et al. J. Med. Genet. 59, 318–327 (2022). - DOI - PubMed