HDAC6 score: to treat or not to treat?

Joschka Hey^{1

2

3}, Maria Llamazares Prada^{1

3}, Christoph Plass^{4

5

6}

Affiliations

¹ Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
² Cancer-Transitional Research and Exchange Program, German-Israeli Helmholtz Research School in Cancer Biology, Heidelberg, Germany.
³ Translational Lung Research Center (TLRC), member of the German Center for Lung Research (DZL), Heidelberg, Germany.
⁴ Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany. c.plass@dkfz.de.
⁵ Cancer-Transitional Research and Exchange Program, German-Israeli Helmholtz Research School in Cancer Biology, Heidelberg, Germany. c.plass@dkfz.de.
⁶ Translational Lung Research Center (TLRC), member of the German Center for Lung Research (DZL), Heidelberg, Germany. c.plass@dkfz.de.

Comment

Joschka Hey et al. Nat Cancer. 2023 Feb.

. 2023 Feb;4(2):156-158.

doi: 10.1038/s43018-022-00494-8.

Joschka Hey^{1

2

3}, Maria Llamazares Prada^{1

3}, Christoph Plass^{4

5

6}

¹ Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
² Cancer-Transitional Research and Exchange Program, German-Israeli Helmholtz Research School in Cancer Biology, Heidelberg, Germany.
³ Translational Lung Research Center (TLRC), member of the German Center for Lung Research (DZL), Heidelberg, Germany.
⁴ Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany. c.plass@dkfz.de.
⁵ Cancer-Transitional Research and Exchange Program, German-Israeli Helmholtz Research School in Cancer Biology, Heidelberg, Germany. c.plass@dkfz.de.
⁶ Translational Lung Research Center (TLRC), member of the German Center for Lung Research (DZL), Heidelberg, Germany. c.plass@dkfz.de.

No abstract available

Comment on

Network-based assessment of HDAC6 activity predicts preclinical and clinical responses to the HDAC6 inhibitor ricolinostat in breast cancer.
Zeleke TZ, Pan Q, Chiuzan C, Onishi M, Li Y, Tan H, Alvarez MJ, Honan E, Yang M, Chia PL, Mukhopadhyay P, Kelly S, Wu R, Fenn K, Trivedi MS, Accordino M, Crew KD, Hershman DL, Maurer M, Jones S, High A, Peng J, Califano A, Kalinsky K, Yu J, Silva J. Zeleke TZ, et al. Nat Cancer. 2023 Feb;4(2):257-275. doi: 10.1038/s43018-022-00489-5. Epub 2022 Dec 30. Nat Cancer. 2023. PMID: 36585452 Free PMC article.

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