Review
doi: 10.1016/j.micinf.2022.105084.
Epub 2022 Dec 28.
Is there a role for herpes simplex virus type 1 in multiple sclerosis?
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- PMID: 36586461
- DOI: 10.1016/j.micinf.2022.105084
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Review
Is there a role for herpes simplex virus type 1 in multiple sclerosis?
Microbes Infect.
2023 Jun.
Free article
Abstract
Numerous studies relate the onset and severity of multiple sclerosis (MS) with viral infections. Herpes simplex virus type 1 (HSV-1), which is neurotropic and highly prevalent in the brain of healthy individuals, has been proposed to relate to MS. Here, we review and discuss the reported connections between HSV-1 and MS.
Keywords: Blood–brain barrier (BBB); Epstein–barr virus (EBV); Experimental autoimmune encephalomyelitis (EAE); Herpes simplex virus (HSV-1); Multiple sclerosis (MS); Neurodegeneration.
Copyright © 2022 The Author(s). Published by Elsevier Masson SAS.. All rights reserved.
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