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. 2023 Apr 1:326:249-261.
doi: 10.1016/j.jad.2022.12.022. Epub 2022 Dec 28.

Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults

Marco Solmi  1 Trevor Thompson  2 Andrés Estradé  3 Agorastos Agorastos  4 Joaquim Radua  5 Samuele Cortese  6 Elena Dragioti  7 Friedrich Leisch  8 Davy Vancampfort  9 Lau Caspar Thygesen  10 Harald Aschauer  11 Monika Schlögelhofer  12 Elena Aschauer  13 Andres Schneeberger  14 Christian G Huber  15 Gregor Hasler  16 Philippe Conus  17 Kim Q Do Cuénod  18 Roland von Känel  19 Gonzalo Arrondo  20 Paolo Fusar-Poli  21 Philip Gorwood  22 Pierre-Michel Llorca  23 Marie-Odile Krebs  24 Elisabetta Scanferla  25 Taishiro Kishimoto  26 Golam Rabbani  27 Karolina Skonieczna-Żydecka  28 Paolo Brambilla  29 Angela Favaro  30 Akihiro Takamiya  31 Leonardo Zoccante  32 Marco Colizzi  33 Julie Bourgin  34 Karol Kamiński  35 Maryam Moghadasin  36 Soraya Seedat  37 Evan Matthews  38 John Wells  39 Emilia Vassilopoulou  40 Ary Gadelha  41 Kuan-Pin Su  42 Jun Soo Kwon  43 Minah Kim  44 Tae Young Lee  45 Oleg Papsuev  46 Denisa Manková  47 Andrea Boscutti  48 Cristiano Gerunda  49 Diego Saccon  50 Elena Righi  51 Francesco Monaco  52 Giovanni Croatto  53 Guido Cereda  54 Jacopo Demurtas  55 Natascia Brondino  56 Nicola Veronese  57 Paolo Enrico  58 Pierluigi Politi  59 Valentina Ciappolino  60 Andrea Pfennig  61 Andreas Bechdolf  62 Andreas Meyer-Lindenberg  63 Kai G Kahl  64 Katharina Domschke  65 Michael Bauer  66 Nikolaos Koutsouleris  67 Sibylle Winter  68 Stefan Borgwardt  69 Istvan Bitter  70 Judit Balazs  71 Pál Czobor  72 Zsolt Unoka  73 Dimitris Mavridis  74 Konstantinos Tsamakis  75 Vasilios P Bozikas  76 Chavit Tunvirachaisakul  77 Michael Maes  78 Teerayuth Rungnirundorn  79 Thitiporn Supasitthumrong  80 Ariful Haque  81 Andre R Brunoni  82 Carlos Gustavo Costardi  83 Felipe Barreto Schuch  84 Guilherme Polanczyk  85 Jhoanne Merlyn Luiz  86 Lais Fonseca  87 Luana V Aparicio  88 Samira S Valvassori  89 Merete Nordentoft  90 Per Vendsborg  91 Sofie Have Hoffmann  92 Jihed Sehli  93 Norman Sartorius  94 Sabina Heuss  95 Daniel Guinart  96 Jane Hamilton  97 John Kane  98 Jose Rubio  99 Michael Sand  100 Ai Koyanagi  101 Aleix Solanes  102 Alvaro Andreu-Bernabeu  103 Antonia San José Cáceres  104 Celso Arango  105 Covadonga M Díaz-Caneja  106 Diego Hidalgo-Mazzei  107 Eduard Vieta  108 Javier Gonzalez-Peñas  109 Lydia Fortea  110 Mara Parellada  111 Miquel A Fullana  112 Norma Verdolini  113 Eva Andrlíková  114 Karolina Janků  115 Mark John Millan  116 Mihaela Honciuc  117 Anna Moniuszko-Malinowska  118 Igor Łoniewski  119 Jerzy Samochowiec  120 Łukasz Kiszkiel  121 Maria Marlicz  122 Paweł Sowa  123 Wojciech Marlicz  124 Georgina Spies  125 Brendon Stubbs  126 Joseph Firth  127 Sarah Sullivan  128 Asli Enez Darcin  129 Hatice Aksu  130 Nesrin Dilbaz  131 Onur Noyan  132 Momoko Kitazawa  133 Shunya Kurokawa  134 Yuki Tazawa  135 Alejandro Anselmi  136 Cecilia Cracco  137 Ana Inés Machado  138 Natalia Estrade  139 Diego De Leo  140 Jackie Curtis  141 Michael Berk  142 Philip Ward  143 Scott Teasdale  144 Simon Rosenbaum  145 Wolfgang Marx  146 Adrian Vasile Horodnic  147 Liviu Oprea  148 Ovidiu Alexinschi  149 Petru Ifteni  150 Serban Turliuc  151 Tudor Ciuhodaru  152 Alexandra Bolos  153 Valentin Matei  154 Dorien H Nieman  155 Iris Sommer  156 Jim van Os  157 Therese van Amelsvoort  158 Ching-Fang Sun  159 Ta-Wei Guu  160 Can Jiao  161 Jieting Zhang  162 Jialin Fan  163 Liye Zou  164 Xin Yu  165 Xinli Chi  166 Philippe de Timary  167 Ruud van Winkel  168 Bernardo Ng  169 Edilberto Pena  170 Ramon Arellano  171 Raquel Roman  172 Thelma Sanchez  173 Larisa Movina  174 Pedro Morgado  175 Sofia Brissos  176 Oleg Aizberg  177 Anna Mosina  178 Damir Krinitski  179 James Mugisha  180 Dena Sadeghi-Bahmani  181 Farshad Sheybani  182 Masoud Sadeghi  183 Samira Hadi  184 Serge Brand  185 Antonia Errazuriz  186 Nicolas Crossley  187 Dragana Ignjatovic Ristic  188 Carlos López-Jaramillo  189 Dimitris Efthymiou  190 Praveenlal Kuttichira  191 Roy Abraham Kallivayalil  192 Afzal Javed  193 Muhammad Iqbal Afridi  194 Bawo James  195 Omonefe Joy Seb-Akahomen  196 Jess Fiedorowicz  197 Andre F Carvalho  198 Jeff Daskalakis  199 Lakshmi N Yatham  200 Lin Yang  201 Tarek Okasha  202 Aïcha Dahdouh  203 Björn Gerdle  204 Jari Tiihonen  205 Jae Il Shin  206 Jinhee Lee  207 Ahmed Mhalla  208 Lotfi Gaha  209 Takoua Brahim  210 Kuanysh Altynbekov  211 Nikolay Negay  212 Saltanat Nurmagambetova  213 Yasser Abu Jamei  214 Mark Weiser  215 Christoph U Correll  216
Affiliations

Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults

Marco Solmi et al. J Affect Disord. .

Abstract

Background: The Collaborative Outcome study on Health and Functioning during Infection Times (COH-FIT; www.coh-fit.com) is an anonymous and global online survey measuring health and functioning during the COVID-19 pandemic. The aim of this study was to test concurrently the validity of COH-FIT items and the internal validity of the co-primary outcome, a composite psychopathology "P-score".

Methods: The COH-FIT survey has been translated into 30 languages (two blind forward-translations, consensus, one independent English back-translation, final harmonization). To measure mental health, 1-4 items ("COH-FIT items") were extracted from validated questionnaires (e.g. Patient Health Questionnaire 9). COH-FIT items measured anxiety, depressive, post-traumatic, obsessive-compulsive, bipolar and psychotic symptoms, as well as stress, sleep and concentration. COH-FIT Items which correlated r ≥ 0.5 with validated companion questionnaires, were initially retained. A P-score factor structure was then identified from these items using exploratory factor analysis (EFA) and confirmatory factor analyses (CFA) on data split into training and validation sets. Consistency of results across languages, gender and age was assessed.

Results: From >150,000 adult responses by May 6th, 2022, a subset of 22,456 completed both COH-FIT items and validated questionnaires. Concurrent validity was consistently demonstrated across different languages for COH-FIT items. CFA confirmed EFA results of five first-order factors (anxiety, depression, post-traumatic, psychotic, psychophysiologic symptoms) and revealed a single second-order factor P-score, with high internal reliability (ω = 0.95). Factor structure was consistent across age and sex.

Conclusions: COH-FIT is a valid instrument to globally measure mental health during infection times. The P-score is a valid measure of multidimensional mental health.

Keywords: COH-FIT; Covid-19; Pandemic; Survey: P-factor: well-being: mental health: psychiatry: psychometric.

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Conflict of interest statement

Conflict of interest Conflict of interest statements of all authors are detailed in Supplementary Table 7.

Figures

Fig. 1
Fig. 1
Pearson's correlation of COH-FIT domain (x-axis) and validation questionnaire (y-axis) measures for each of the COH-FIT domains.
Fig. 2
Fig. 2
Factor structure of the composite psychopathology P-Score from confirmatory factor analysis.

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