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Review
. 2023 Jun;43(6):798-805.
doi: 10.1002/pd.6299. Epub 2023 Jan 12.

Fetal arthrogryposis-what do we tell the prospective parents?

Isabel Filges  1 , Stephanie Jünemann  2 , Elke Viehweger  3 , Sevgi Tercanli  4
Affiliations
Review

Fetal arthrogryposis-what do we tell the prospective parents?

Isabel Filges et al. Prenat Diagn. 2023 Jun.

Abstract

Arthrogryposis, also termed arthrogryposis multiplex congenita, is a descriptive term for conditions with multiple congenital contractures (MCC). The etiology is extremely heterogeneous. More than 400 specific disorders have been identified so far, which may lead to or are associated with MCC and/or fetal hypo- and akinesia as a clinical sign. With improved sensitivity of prenatal ultrasound and expanding prenatal diagnostic options, clinicians are tasked with providing early detection in order to counsel the prospective parents regarding further prenatal diagnostic as well as management options. We summarize the most important knowledge to raise awareness for early detection in pregnancy. We review essential points for counseling when MCC is detected in order to provide answers to common questions, which, however, cannot replace interdisciplinary expert opinion in the individual case.

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References

REFERENCES

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