Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug 25;31(4):244-250.
doi: 10.1055/s-0042-1751234. eCollection 2022 Dec.

Epidemiology, Pathophysiology, and Management of Coronary Artery Disease in the Elderly

Kahtan Fadah  1 , Aimee Hechanova  1 , Debabrata Mukherjee  2
Affiliations

Epidemiology, Pathophysiology, and Management of Coronary Artery Disease in the Elderly

Kahtan Fadah et al. Int J Angiol. .

Abstract

Elderly patients over the age of ≥ 75 years are especially susceptible to coronary artery disease (CAD) as age is an important nonmodifiable risk factors for atherosclerosis and a predictor of poorer outcomes. In fact, CAD is a major cause of mortality and morbidity in this population. Due to concerns of functional frailty, comorbidities, and patient preference of conservative to no treatment have played a role in reducing the interest in pursuing prospective studies in this high-risk group. In this review, we provide an overview of the epidemiology, pathophysiology, and management of CAD in older adults.

Keywords: aging; atherosclerosis; coronary artery disease; elderly; frailty; revascularization.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None declared.

References

    1. Writing Group Members ; American Heart Association Statistics Committee ; Stroke Statistics Subcommittee . Mozaffarian D, Benjamin E J, Go A S. Heart Disease and Stroke Statistics-2016 update: a report from the American Heart Association. Circulation. 2016;133(04):e38–e360. - PubMed
    1. CORE investigators . Phrommintikul A, Krittayaphong R, Wongcharoen W. Management and risk factor control of coronary artery disease in elderly versus nonelderly: a multicenter registry. J Geriatr Cardiol. 2016;13(12):954–959. - PMC - PubMed
    1. Rodgers J L, Jones J, Bolleddu S I. Cardiovascular risks associated with gender and aging. J Cardiovasc Dev Dis. 2019;6(02):E19. - PMC - PubMed
    1. Administration on Aging (AoA), U.S. Department of Health and Human Service. 2020 PROFILE OF OLDER AMERICANS, May 2021 Available athttps://acl.gov/sites/default/files/Aging%20and%20Disability%20in%20Amer...
    1. Forman D E, Rich M W, Alexander K P. Cardiac care for older adults. Time for a new paradigm. J Am Coll Cardiol. 2011;57(18):1801–1810. - PMC - PubMed