Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Dec 28;2022(12):rjac589.
doi: 10.1093/jscr/rjac589. eCollection 2022 Dec.

Cutaneous presentation of metastatic pancreatic cancer

Affiliations
Case Reports

Cutaneous presentation of metastatic pancreatic cancer

Mohammed Abdelaziz et al. J Surg Case Rep. .

Abstract

Pancreatic cancer typically presents with a cholestatic picture of jaundice, bloating and bowel changes, secondary to the obstruction of the biliary system. In tail of pancreas metastases, this clinical presentation may be absent, meaning that the disease progression can be more insidious. Cutaneous spread in pancreatic malignancies is often iatrogenic due to direct spread from the tumour site during diagnostic sampling or surgery. Rarely, cutaneous spread can be noted at distant sites, which is associated with widespread disease dissemination and poor prognostic outcomes. Our case focusses on a patient who developed metastatic spread to the chin, as a first presentation, with no other significant associated symptoms identified.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Axial STIR MRI image of lesion at level of chin.
Figure 2
Figure 2
FDG PET CT imaging showing locations of metastases.
Figure 3
Figure 3
Axial CT imaging showing malignant primary at pancreatic tail.
Figure 4
Figure 4
Axial FDG PET CT showing liver metasteses.

References

    1. Miulescu R, Balaban DV, Sandru F, Jinga M. Cutaneous manifestations in pancreatic diseases—a review. J Clin Med 2020;9:2611. - PMC - PubMed
    1. Zhou HY, Wang XB, Gao F, Bu B, Zhang S, Wang Z. Cutaneous metastasis from pancreatic cancer: a case report and systematic review of the literature. Oncol Lett 2014;8:2654–60. - PMC - PubMed
    1. Kotsantis I, Economopoulou P, Dritsakos K, Oikonomopoulos N, Bakogeorgos M, Rapti C, et al. . Extensive cutaneous metastases of pancreatic adenocarcinoma: a case report and review of the literature. Clin Case Rep 2017;5:51–6. - PMC - PubMed

Publication types