Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Dec 21:9:82-84.
doi: 10.18632/oncoscience.571. eCollection 2022.

Rapamycin in the context of Pascal's Wager: generative pre-trained transformer perspective

Affiliations

Rapamycin in the context of Pascal's Wager: generative pre-trained transformer perspective

ChatGPT Generative Pre-trained Transformer et al. Oncoscience. .

Abstract

Large language models utilizing transformer neural networks and other deep learning architectures demonstrated unprecedented results in many tasks previously accessible only to human intelligence. In this article, we collaborate with ChatGPT, an AI model developed by OpenAI to speculate on the applications of Rapamycin, in the context of Pascal's Wager philosophical argument commonly utilized to justify the belief in god. In response to the query "Write an exhaustive research perspective on why taking Rapamycin may be more beneficial than not taking Rapamycin from the perspective of Pascal's wager" ChatGPT provided the pros and cons for the use of Rapamycin considering the preclinical evidence of potential life extension in animals. This article demonstrates the potential of ChatGPT to produce complex philosophical arguments and should not be used for any off-label use of Rapamycin.

Keywords: Pascal’s Wager; Rapamycin; artificial intelligence; longevity medicine; philosophy.

PubMed Disclaimer

Conflict of interest statement

CONFLICTS OF INTEREST Authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1. ChatGPT output on Rapamycin in the context of Pascal’s wager - ChatGPT output in response to the query.

References

    1. Blagosklonny MV. Rapamycin for longevity: opinion article. Aging (Albany NY). 2019; 11:8048–67. 10.18632/aging.102355. - DOI - PMC - PubMed
    1. Blagosklonny MV. An anti-aging drug today: from senescence-promoting genes to anti-aging pill. Drug Discov Today. 2007; 12:218–24. 10.1016/j.drudis.2007.01.004. - DOI - PubMed
    1. Rapamycin News. 2022. https://www.rapamycin.news/t/80-of-longevity-experts-predict-significant.... [Accessed 14 December 2022].
    1. ChatGPT. OpenAI. 2022. Available at: https://beta.openai.com/docs/models/chatgpt. [Accessed 14 December 2022].
    1. Brown T, Mann B, Ryder N, Subbiah M, Kaplan JD, Dhariwal P, Neelakantan A, Shyam P, Sastry G, Askell A, Agarwal S, Herbert-Voss A, Krueger G, Henighan T, et al.. Language Models are Few-Shot Learners. Nature. 2020; 586:557–61. 10.48550/arXiv.2005.14165. - DOI