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. 2022 Dec 19;8(12):e12430.
doi: 10.1016/j.heliyon.2022.e12430. eCollection 2022 Dec.

Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study

Yue Qian  1 , Jian-Kun Zhu  1 , Bai-Ling Hou  2 , Yu-E Sun  2 , Xiao-Ping Gu  1 , Zheng-Liang Ma  1
Affiliations

Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study

Yue Qian et al. Heliyon. .

Abstract

Objective: To explore potential risk factors of postoperative nausea and vomiting (PONV) following ambulatory surgery.

Method: Clinical data of 1670 cases receiving ambulatory surgery in Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School from September 2017 to December 2019 were retrospectively analyzed. They were categorized to PONV group and non-PONV group, and perioperative data in both groups were analyzed for assessing risk factors of PONV following ambulatory laparoscopy.

Results: There were 156/1,670 (9.3%) PONV cases, and the female and male incidence in recruited cases was 12.0% and 6.0%, respectively. Analyses on perioperative data of them identified that female gender [adjusted odds ratio (aOR) = 2.060, P < 0.001], operation time >1 h (aOR = 1.554, P = 0.011), postoperative pain at rest (aOR = 1.909, P = 0.013) and postoperative pain during activities (aOR = 3.512, P < 0.001) were independent risk factors of PONV following ambulatory surgery. Furthermore, postoperative pain at rest and during activities were linearly, positively correlated to the incidence of PONV.

Conclusion: Female gender, operation time >1 h and postoperative pain are closely related with the incidence of PONV following ambulatory surgery. Alleviating postoperative pain properly is one of the methods to reduce risk factors of PONV following ambulatory surgery.

Keywords: Ambulatory surgery; Postoperative nausea and vomiting; Postoperative pain.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
ROC curves depicting the discrimination of the model in distinguishing PONV cases from patients receiving ambulatory surgery.
Figure 2
Figure 2
Hosmer-Lemeshow goodness-of-fit test verifying the calibration of the estimated model in distinguishing PONV cases from patients receiving ambulatory surgery.
Figure 3
Figure 3
Correlation between postoperative VAS score at rest (A) and during activities (B) and the incidence of PONV following ambulatory surgery.
See this image and copyright information in PMC

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