Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Dec 19;8(12):e12430.
doi: 10.1016/j.heliyon.2022.e12430. eCollection 2022 Dec.

Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study

Yue Qian  1 , Jian-Kun Zhu  1 , Bai-Ling Hou  2 , Yu-E Sun  2 , Xiao-Ping Gu  1 , Zheng-Liang Ma  1
Affiliations

Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study

Yue Qian et al. Heliyon. .

Abstract

Objective: To explore potential risk factors of postoperative nausea and vomiting (PONV) following ambulatory surgery.

Method: Clinical data of 1670 cases receiving ambulatory surgery in Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School from September 2017 to December 2019 were retrospectively analyzed. They were categorized to PONV group and non-PONV group, and perioperative data in both groups were analyzed for assessing risk factors of PONV following ambulatory laparoscopy.

Results: There were 156/1,670 (9.3%) PONV cases, and the female and male incidence in recruited cases was 12.0% and 6.0%, respectively. Analyses on perioperative data of them identified that female gender [adjusted odds ratio (aOR) = 2.060, P < 0.001], operation time >1 h (aOR = 1.554, P = 0.011), postoperative pain at rest (aOR = 1.909, P = 0.013) and postoperative pain during activities (aOR = 3.512, P < 0.001) were independent risk factors of PONV following ambulatory surgery. Furthermore, postoperative pain at rest and during activities were linearly, positively correlated to the incidence of PONV.

Conclusion: Female gender, operation time >1 h and postoperative pain are closely related with the incidence of PONV following ambulatory surgery. Alleviating postoperative pain properly is one of the methods to reduce risk factors of PONV following ambulatory surgery.

Keywords: Ambulatory surgery; Postoperative nausea and vomiting; Postoperative pain.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
ROC curves depicting the discrimination of the model in distinguishing PONV cases from patients receiving ambulatory surgery.
Figure 2
Figure 2
Hosmer-Lemeshow goodness-of-fit test verifying the calibration of the estimated model in distinguishing PONV cases from patients receiving ambulatory surgery.
Figure 3
Figure 3
Correlation between postoperative VAS score at rest (A) and during activities (B) and the incidence of PONV following ambulatory surgery.
See this image and copyright information in PMC

References

    1. Nicoll J.H. The surgery of infancy. Pediatric Anesthesia. 1909;2(2542):753–754.
    1. Kehlet H. Enhanced Recovery after Surgery (ERAS): good for now, but what about the future? Can. J. Anaesth. 2015;62(2):99–104. - PubMed
    1. Grant M.C., Yang D., Wu C.L., et al. Impact of enhanced recovery after surgery and fast track surgery pathways on healthcare-associated infections: results from a systematic review and meta-analysis. Ann. Surg. 2017;265(1):68–79. - PubMed
    1. Finch Catherine, Parkosewich Janet A., Perrone Diane, et al. Incidence, timing, and factors associated with postoperative nausea and vomiting in the ambulatory surgery setting. J. Perianesth. Nurs. 2019;34(6):1146–1155. - PubMed
    1. Gupta D., Haber H. Emetogenicity-risk procedures in same day surgery center of an academic university hospital in United States: a retrospective cost-audit of postoperative nausea vomiting management. Middle East J. Anesthesiol. 2014;22(5):493–502. - PubMed

LinkOut - more resources