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Review
. 2022 Dec 7;8(12):e12013.
doi: 10.1016/j.heliyon.2022.e12013. eCollection 2022 Dec.

Chemical characteristics of the sesquiterpenes and diterpenes from Lauraceae family and their multifaceted health benefits: A review

Haowei Feng  1 , Yiping Jiang  2 , Huihui Cao  1   3 , Yuqi Shu  1 , Xiaoyu Yang  1 , Daoqi Zhu  4 , Meng Shao  1   5
Affiliations
Review

Chemical characteristics of the sesquiterpenes and diterpenes from Lauraceae family and their multifaceted health benefits: A review

Haowei Feng et al. Heliyon. .

Abstract

Lauraceae is a large family with significant economic and medicinal value. Bioactive ingredients from Lauraceae plants have contributed greatly to medicines, food nutrients and fine chemical products. In recent years, quite a few sesquiterpenes and diterpenes with unique structures have been achieved from Lauraceae and their potential benefits are embodied in a wide range of health areas. To our knowledge, there is no review to summarizes these constituents and their biological effects systematically. This current work aims to classify and ascribe the structural types and bioactivities of the identified sesquiterpenes and diterpenes. Herein, a total of 362 sesquiterpenes and 69 diterpenes were comprehensively complied. The various bioactivities could be recognized as cytotoxicity, anti-proliferation and/or anti-apoptosis, anti-inflammation, anti-oxidation, anti-bacterium, etc. This updated data could serve as a catalysis of these sesquiterpenes and diterpenes for the future medical and industrial applications.

Keywords: Biological activities; Diterpenes; Lauraceae; Sesquiterpenes; Traditional application.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Distribution of Lauraceae plants around the world (the red zone, original map downloaded from http://bzdt.ch.mnr.gov.cn/index.html).
Figure 2
Figure 2
Three representative Lauracea plants in China. (A) Cinnamomum cassia Presl; (B) Cinnamomum burmannii (Nees) BL; (C) Cinnamomum camphora (L.); Presl.
Figure 3
Figure 3
Chemical structures of the sesquiterpenes isolated from Lauraceae.
Figure 4
Figure 4
Eight known carbon skeletal types of diterpenoids from C. cassia and chemical structures of the diterpenes isolated from Lauraceae.
Figure 5
Figure 5
The proposed biosynthetic pathways of compounds (388, 389, 401–403 and 417).
See this image and copyright information in PMC

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