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. 2022 Dec 15:13:960029.
doi: 10.3389/fpsyg.2022.960029. eCollection 2022.

The association between sleep problems and general quality of life in cancer patients and in the general population

Dirk Hofmeister  1 , Thomas Schulte  2 , Anja Mehnert-Theuerkauf  1 , Kristina Geue  1 , Markus Zenger  3   4 , Peter Esser  1 , Heide Götze  1 , Andreas Hinz  1
Affiliations

The association between sleep problems and general quality of life in cancer patients and in the general population

Dirk Hofmeister et al. Front Psychol. .

Abstract

Objective: It is well-known that patients with cancer frequently experience sleep problems, and that sleep quality is associated with general quality of life (QoL). The aims of this study were to analyze the relationship between sleep problems and other components of QoL in more detail and to investigate sex and age differences in sleep quality in cancer patients in comparison with the general population.

Method: This study comprised one general population sample (n = 4,476) and eight samples with cancer patients (n between 323 and 4,020). Sleep Quality was measured using the QoL questionnaire EORTC QLQ-C30.

Results: All of the cancer patient groups reported more sleep problems than the general population. Sleep problems were associated with all facets of QoL both in cancer patients and in the general population. The highest associations were found in cancer patients for fatigue (r = 0.52) and emotional functioning (r = -0.47). The association between sleep quality and general QoL was lower in the cancer samples (r = -0.37) than in the general population (r = -0.46). Female cancer patients reported markedly more sleep problems than male patients did (d = 0.45), while this sex difference was lower in the general population (d = 0.15). In contrast to the general population, younger cancer patients had greater trouble sleeping than older patients did (d = -0.17).

Conclusion: The results underline the significance of the role mental factors play in sleep problems. Health care providers should pay special attention to female patients and younger patients concerning this issue.

Keywords: age differences; cancer; insomnia; quality of life; sex differences; sleep loss.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. Aaronson N. K., Ahmedzai S., Bergman B., Bullinger M., Cull A., Duez N. J., et al. . (1993). The European-organization-for-research-and-treatment-of-cancer QLQ-C30- a quality-of-life instrument for use in international clinical trials in oncology. J. Natl. Cancer Inst. 85, 365–376. doi: 10.1093/jnci/85.5.365, PMID: - DOI - PubMed
    1. Akman T., Yavuzsen T., Sevgen Z., Ellidokuz H., Yilmaz A. U. (2015). Evaluation of sleep disorders in cancer patients based on Pittsburgh sleep quality index. Eur. J. Cancer Care 24, 553–559. doi: 10.1111/ecc.12296 - DOI - PubMed
    1. Ancoli-Israel S. (2009). Recognition and treatment of sleep disturbances in cancer. J. Clin. Oncol. 27, 5864–5866. doi: 10.1200/JCO.2009.24.5993 - DOI - PubMed
    1. Ancoli-Israel S., Liu L., Rissling M., Natarajan L., Neikrug A. B., Palmer B. W., et al. . (2014). Sleep, fatigue, depression, and circadian activity rhythms in women with breast cancer before and after treatment. A 1-year longitudinal study. Support Care Cancer 22, 2535–2545. doi: 10.1007/s00520-014-2204-5, PMID: - DOI - PMC - PubMed
    1. Aronsen S., Conway R., Lally P., Roberts A., Croker H., Beeken R. J., et al. . (2022). Determinants of sleep quality in 5835 individuals living with and beyond breast, prostate, and colorectal cancer: a cross-sectional survey. J. Cancer Surviv. 16, 1489–1501. doi: 10.1007/s11764-021-01127-2, PMID: - DOI - PubMed

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