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. 2023 Jun:7:72-76.
doi: 10.1016/j.ijregi.2022.12.009. Epub 2022 Dec 29.

COVID-19 inpatient treatments and outcomes during the conflict in Syria: an observational cohort study

Ibrahim Antoun  1   2 , Alkassem Alkhayer  3 , Yalaa Aboud  3 , Hiba Alkhayer  4 , Ahmed Kotb  1   2 , Amer Alkhayer  3 , Joseph Barker  1   2   5 , Riyaz Somani  1   2 , G Andre Ng  1   2   5
Affiliations

COVID-19 inpatient treatments and outcomes during the conflict in Syria: an observational cohort study

Ibrahim Antoun et al. IJID Reg. 2023 Jun.

Abstract

Background: During the COVID-19 pandemic, countries undergoing conflict have faced difficulties in mounting an effective health response. This observational cohort study describes the treatments and outcomes for inpatients with COVID-19 in the Syrian city of Latakia.

Design and methods: A single-centre observational cohort study was conducted at Tishreen University Hospital, involving all patients over 18 admitted between October 1 and December 31, 2021 with a positive RT-PCR test for SARS-CoV-2. Clinical features, investigations, treatments, and outcomes were reported.

Results: In total, 149 patients fitted the study criteria. Only one patient was double vaccinated against COVID-19. Oxygen supplementation was required in 87% (n = 130) of participants. Invasive mechanical ventilation was required in 4% (n = 5). Therapeutic anticoagulation was administered in 97.3% (n = 144). Intravenous dexamethasone was received by 97.3% (n = 145) of participants. All patients received empiric antibiotic treatment. In-hospital mortality was 48.4% (n = 72), while only 40.9% (n = 61) were discharged during the study period.

Conclusion: The pandemic has placed a compromised Syrian healthcare system under more significant strain. This requires urgent international relief efforts from health agencies in order to aid the pandemic response.

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Conflict of interest statement

No conflicts of interest to report.

Figures

Figure 1
Fig. 1
Summary of inpatient treatments and outcomes.
See this image and copyright information in PMC

References

    1. Slim H, Trombetta L. Co-ordinated Accountability and Lessons Learning (CALL) Initiative, IASC Inter-Agency Humanitarian Evaluations Steering Group; New York: 2014. Syria crisis common context analysis.
    1. Ekzayez A, Khalil M, Jasiem M, et al. COVID-19 response in northwest Syria: innovation and community engagement in a complex conflict. Journal of Public Health. 2020;42(3):504–509. doi: 10.1093/pubmed/fdaa068. - DOI - PMC - PubMed
    1. Mercy Corps; 2021. The facts: what you need to know about the Syria crisis [Internet]https://www.mercycorps.org/blog/quick-facts-syria-crisis [cited March 20, 2022]. Available from:
    1. World Health Organization . 2022. From preparedness to vaccination: WHO Syria — special COVID-19 report [Internet]https://reliefweb.int/report/syrian-arab-republic/preparedness-vaccinati... a[cited September 23, 2022]. Available from:
    1. Vandenbroucke JP, Von Elm E, Altman DG, Gøtzsche PC, Mulrow CD, Pocock SJ, et al. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. PLoS Medicine. 2007;4(10):e297. doi: 10.1371/journal.pmed.0040297. - DOI - PMC - PubMed