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. 1987 Jun;43(2):223-7.

Embryotoxic effects of sodium metavanadate administered to rats during organogenesis

J L Paternain  1 , J L Domingo, J M Llobet, J Corbella
Affiliations
  • PMID: 3659548

Embryotoxic effects of sodium metavanadate administered to rats during organogenesis

J L Paternain et al. Rev Esp Fisiol. 1987 Jun.

Abstract

Pregnant Sprague-Dawley rats were given orally a daily dose of 0, 5, 10 or 20 mg NaVO3/kg from the sixth through the fourteenth day of pregnancy. Fetal examinations were performed on day 20 of gestation. Sodium metavanadate was neither embryolethal nor teratogenic in rats when administered orally at 20 mg/kg/day or lower. Nevertheless, this dose was embryotoxic.

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