High prevalence of pathogenic variants in Japanese children with steroid-resistant nephrotic syndrome without edema detected by urine screening program

Affiliations

¹ Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-Ku, Saitama City, Saitama, 330-8777, Japan. f_shuich@d2.dion.ne.jp.
² Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-Ku, Saitama City, Saitama, 330-8777, Japan.

Comment

Shuichiro Fujinaga et al. Pediatr Nephrol. 2023 May.

. 2023 May;38(5):1693-1694.

doi: 10.1007/s00467-022-05863-0. Epub 2023 Jan 4.

¹ Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-Ku, Saitama City, Saitama, 330-8777, Japan. f_shuich@d2.dion.ne.jp.
² Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-Ku, Saitama City, Saitama, 330-8777, Japan.

No abstract available

Comment in

Ascertaining pathogenicity of genetic variants: caution required.
Arslan Z, Watson E, Bockenhauer D. Arslan Z, et al. Pediatr Nephrol. 2023 May;38(5):1695-1696. doi: 10.1007/s00467-023-05909-x. Epub 2023 Feb 21. Pediatr Nephrol. 2023. PMID: 36809442 No abstract available.
Necessity of genetic testing on asymptomatic proteinuria before the progression of nephrotic syndrome in children with focal segmental glomerulosclerosis.
Fujinaga S, Oba D. Fujinaga S, et al. Pediatr Nephrol. 2023 Sep;38(9):3199-3200. doi: 10.1007/s00467-023-06016-7. Epub 2023 May 10. Pediatr Nephrol. 2023. PMID: 37162573 No abstract available.

Mendelian steroid resistant nephrotic syndrome in childhood: is it as common as reported?
Arslan Z, Webb H, Ashton E, Foxler B, Tullus K, Waters A, Bockenhauer D. Arslan Z, et al. Pediatr Nephrol. 2023 Apr;38(4):1051-1056. doi: 10.1007/s00467-022-05569-3. Epub 2022 Jul 8. Pediatr Nephrol. 2023. PMID: 35802272

1. Arslan Z, Webb H, Ashton E, Foxler B, Tullus K, Waters A, Bockenhauer D (2022) Mendelian steroid resistant nephrotic syndrome in childhood: is it as common as reported? Pediatr Nephrol. https://doi.org/10.1007/s00467-022-05569-3 - DOI - PubMed
1. Nagano C, Hara S, Yoshikawa N, Takeda A, Gotoh Y, Hamada R, Matsuoka K, Yamamoto M, Fujinaga S, Sakuraya K, Kamei K, Hamasaki Y, Oguchi H, Araki Y, Ogawa Y, Okamoto T, Ito S, Tanaka S, Kaito H, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Horinouchi T, Yamamura T, Nagase H, Iijima K, Nozu K (2022) Clinical, pathological, and genetic characteristics in patients with focal segmental glomerulosclerosis. Kidney360 3:1384–1393
1. Watanabe Y, Fujinaga S, Sakuraya K, Ikeda H, Nozu K (2022) Clinical, pathological, and genetic characteristics of cases with asymptomatic proteinuria not manifesting nephrotic syndrome at onset: a single-center retrospective study. Clin Exp Nephrol 26:453–459 - DOI - PubMed