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Comment
. 2023 Feb;19(2):61.
doi: 10.1038/s41584-022-00899-w.

Ferritin-induced NETs lead to cytokine storm in AOSD

Sarah Onuora  1
Affiliations
Comment

Ferritin-induced NETs lead to cytokine storm in AOSD

Sarah Onuora. Nat Rev Rheumatol. 2023 Feb.

Abstract

New research reveals that ferritin has an essential role in neutrophil extracellular trap (NET)-mediated inflammation, and suggests that NETs or the ferritin receptor MSR1 could be targeted for the treatment of adult-onset Still disease.

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References

    1. Jia J, et al. Ferritin triggers neutrophil extracellular trap-mediated cytokine storm through Msr1 contributing to adult-onset Still’s disease pathogenesis. Nat. Commun. 2022;13:6804. doi: 10.1038/s41467-022-34560-7. - DOI - PMC - PubMed

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