Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Apr 1;28(2):139-144.
doi: 10.1097/MOT.0000000000001045. Epub 2023 Jan 3.

Simultaneous thoracic and abdominal donation after circulatory death organ recovery: the abdominal surgeon's perspective

Affiliations
Review

Simultaneous thoracic and abdominal donation after circulatory death organ recovery: the abdominal surgeon's perspective

Carrie Thiessen et al. Curr Opin Organ Transplant. .

Abstract

Purpose of the review: To summarize the international experience with heart-liver (joint) donation after circulatory death (DCD) procurements and to explore the technical challenges in joint abdominal and thoracic DCD procurement.

Recent findings: Following completion of the Donors After Circulatory Death Heart Trial in the US, combined thoracic and abdominal DCD is poised to become the standard of care, expanding access to life-saving heart and lung allografts. DCD heart procurement relies on collection of donor blood for priming of the normothermic perfusion pump, which delays cooling of abdominal organs and increases risk of ischemic injury. We review the effect of donor ischemia time on abdominal organs, with several proposed technical solutions to optimize transplant outcomes for all organs.

Summary: The strategies reviewed in this manuscript may inform clinical decision-making, preoperative coordination between thoracic and abdominal procurement teams, and surgical technique for joint DCD procurements. Several approaches to organ procurement organization (OPO) and national policy, as well as future areas of focus for research are proposed.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Box 1
Box 1
no caption available

References

    1. Abt PL, Fisher CA, Singhal AK. Donation after cardiac death in the US: history and use. J Am Coll Surg 2006; 203:208–225. - PubMed
    1. Institute of Medicine. Non-heart-beating organ transplantation: practice and protocols. Washington DC: National Academy Press; 2000. - PubMed
    1. Potts JT, Herdman R. Non-heart-beating organ transplantation: medical and ethical issues in procurement. Washington DC: National Academy Press; 1997. - PubMed
    1. University of Pittsburgh Medical Center policy and procedure manual. Management of terminally ill patients who may become organ donors after death. Kennedy Inst Ethics J 1993; 3:A1–15. - PubMed
    1. Israni AK, Zaun D, Rosendale JD, et al. . OPTN/SRTR 2019 annual data report: deceased organ donors. Am J Transplant 2021; 21: (Suppl 2): 521–558. - PubMed