Sticking to your side: A niche for the development of ipsilateral retinal projections
- PMID: 36603550
- DOI: 10.1016/j.neuron.2022.12.017
Sticking to your side: A niche for the development of ipsilateral retinal projections
Abstract
Visual impairments in albinism result from decreased ipsilateral retinal projections. In this issue of Neuron, Slavi, Balasubramanian, and colleagues1 demonstrate how low CyclinD2 in the ciliary marginal zone perturbs generation of ipsilaterally projecting RGCs and that restoring CyclinD2 improves vision in albino mice.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
-
CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism.Neuron. 2023 Jan 4;111(1):49-64.e5. doi: 10.1016/j.neuron.2022.10.025. Epub 2022 Nov 8. Neuron. 2023. PMID: 36351424 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
