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Comment
. 2023 Jan;103(1):28-30.
doi: 10.1016/j.kint.2022.09.018.

Youth with single kidneys-what is the evidence of risk?

Julie R Ingelfinger  1
Affiliations
Comment

Youth with single kidneys-what is the evidence of risk?

Julie R Ingelfinger. Kidney Int. 2023 Jan.

Abstract

Children and youth with a congenital or acquired single functioning kidney are at risk for development of kidney injury and chronic kidney disease. How best to use surrogate measures associated with risk factors poses many problems. The risk of progressive kidney disease for those with a single functioning kidney varies, and how to assess it remains imperfect. Developing better measures to determine the risk of chronic kidney disease-renal functional reserve and imaging that includes nephron number-may be within reach and would likely positively affect the outcome.

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Comment on

  • Uncovering risk factors for kidney injury in children with a solitary functioning kidney.
    Groen In 't Woud S, Roeleveld N, Westland R, Renkema KY, Steffens MG, Gracchi V, Lilien MR, van Wijk JAE, Feitz WFJ, Schreuder MF, van der Zanden LFM; Solitary Functioning Kidney: Aetiology and Prognosis (SOFIA) study group. Groen In 't Woud S, et al. Kidney Int. 2023 Jan;103(1):156-165. doi: 10.1016/j.kint.2022.09.028. Epub 2022 Oct 28. Kidney Int. 2023. PMID: 36374825

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