Determination of cocaine in human hair by gas chromatography/mass spectrometry
- PMID: 3660952
- DOI: 10.1007/BF00201228
Determination of cocaine in human hair by gas chromatography/mass spectrometry
Abstract
A qualitative method for the determination of cocaine alone without its metabolites in human hair by gas chromatography/mass spectrometry (GC/MS) was developed. The assay used helium as carrier gas, a 30-m bonded phase fused silica OV-1 capillary column, and solid injection at 290 degrees C evaporator temperature. The cocaine concentrations in hair were determined also by radioimmunoassay (RIA). The values obtained are the sum of cocaine and its metabolites. Both GC/MS and RIA meet the requirements for the determination of drug abuse by two different methods in forensic science.
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