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Review
. 2022 Dec 31;15(1):298.
doi: 10.3390/cancers15010298.

Special Techniques of Adjuvant Breast Carcinoma Radiotherapy

Iveta Kolářová  1   2 , Bohuslav Melichar  3 , Jaroslav Vaňásek  2   4 , Igor Sirák  1 , Jiří Petera  1 , Kateřina Horáčková  2 , Denisa Pohanková  1 , Zuzana Šinkorová  5 , Oldřich Hošek  2 , Milan Vošmik  1
Affiliations
Review

Special Techniques of Adjuvant Breast Carcinoma Radiotherapy

Iveta Kolářová et al. Cancers (Basel). .

Abstract

Modern radiotherapy techniques are designed to permit reduced irradiation of healthy tissue, resulting in a diminished risk of adverse effects and shortened recovery times. Several randomized studies have demonstrated the benefits of increased dosage to the tumor bed area in combination with whole breast irradiation (WBI). Conventional WBI treatment following breast-conserving procedures, which required 5-7 weeks of daily treatments, has been reduced to 3-4 weeks when using hyperfractionated regimens. The dosage administration improves local control, albeit with poorer cosmesis. The method of accelerated partial breast irradiation (APBI) shortens the treatment period whilst reducing the irradiated volume. APBI can be delivered using intraoperative radiation, brachytherapy, or external beam radiotherapy. Currently available data support the use of external beam partial breast irradiation in selected patients. Modern radiotherapy techniques make it possible to achieve favorable cosmesis in most patients undergoing immediate breast reconstruction surgery, and studies confirm that current methods of external beam radiation allow an acceptable coverage of target volumes both in the reconstructed breast and in the regional lymphatic nodes.

Keywords: accelerated partial breast irradiation; adjuvant radiotherapy; boost; breast cancer.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
3D visualization of multicathether interstitial APBI technique from different viewing angles, delineation and dose calculation: interstitial catheters—white, CTV—orange, skin—light green, surgical clips and skin incision—yellow. Dose 3.4 Gy per fraction. Dose distribution presented by the color distribution: V150 (5.1 Gy)—red, V100 (3.4 Gy)—green, 2 Gy—blue.
Figure 2
Figure 2
3D visualization of external beam PBI technique from different viewing angles, delineation and dose distribution: heart—red, left ventricle and left anterior descending artery—white, left breast—orange, left lung—blue. Photon dose distribution produced by LINAC is presented by the color distribution: 95—107% of prescribed dose; 40 Gy/15 fractions.
Figure 3
Figure 3
Breast irradiation after radical mastectomy with silicone implant insertion. A dose greater than 90% of the prescribed dose is displayed in color. The maximum dose in this slice is 105.6 % of the prescribed dose.
See this image and copyright information in PMC

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