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Editorial
. 2022 Dec 30;15(1):171.
doi: 10.3390/nu15010171.

A Pleiotropic Nuclear Hormone Labelled Hundred Years Ago Vitamin D

Carsten Carlberg  1   2
Affiliations
Editorial

A Pleiotropic Nuclear Hormone Labelled Hundred Years Ago Vitamin D

Carsten Carlberg. Nutrients. .

Abstract

This year we are celebrating 100 years of the naming of vitamin D, but the molecule is, in fact, more than one billion years old [...].

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Figure 1
Figure 1
Expression of the VDR gene in 54 different human tissues. Normalized RNA sequencing (RNA-seq) data are shown in TPM (transcripts per million), where all isoforms were collapsed into a single gene. Box plots display the median as well as 25th and 75th percentiles. Points indicate outliers that are 1.5 times above or below interquartile range. Data are based on GTEx analysis release V8 (dbGaP Accession phs000424.v8.p2) [31].
Figure 2
Figure 2
Pleiotropic physiological functions of vitamin D. Vitamin D3 (center) can be produced endogenously in UV-B exposed skin. Via its metabolite 1,25(OH)2D3, vitamin D3 activates VDR in various tissues and cell types, where it regulates the indicated major physiological functions.
See this image and copyright information in PMC

References

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