Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Dec 21:10:1091580.
doi: 10.3389/fcell.2022.1091580. eCollection 2022.

Wilson's disease: Food therapy out of trace elements

Wen-Jie Li  1   2 , Huan-Ling Chen  1 , Bin Wang  1 , Lei Yao  1 , Xiao-Ping Wang  1   3
Affiliations
Review

Wilson's disease: Food therapy out of trace elements

Wen-Jie Li et al. Front Cell Dev Biol. .

Abstract

Hepatolenticular degeneration, also known as Wilson's disease (WD), is an autosomal recessive inheritance nervous disorder of copper metabolism. The treatment of hepatolenticular degeneration emphasizes the combination of medical therapy and dietary therapy, such as a high zinc, low copper and sulfhydryl rich diet. Food therapy of WD based on trace elements is presented in this paper.

Keywords: Wilson’s disease; copper; food therapy; metal; protein; trace elements.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Our results of MRI-QSM signals: iron/copper related Magnetic Susceptibility in the Deep Gray Matter Nuclei of Wilson’s Disease. Note: CN: caudate nucleus; GP: globus pallidus; PUT: putamen; SN: substantia; RN:rednucleus; DN: dental nucleus.
See this image and copyright information in PMC

References

    1. Brewer G., Yuzbasiyan-Gurkan V. (1992). Wilson disease. Medicine 71 (3), 139–164. 10.1097/00005792-199205000-00004 - DOI - PubMed
    1. Cai H., Cheng X., Wang X. P. (2022). ATP7B gene therapy of autologous reprogrammed hepatocytes alleviates copper accumulation in a mouse model of Wilson's disease. Hepatology 76 (4), 1046–1057. 10.1002/hep.32484 - DOI - PMC - PubMed
    1. Cao Z. Q., Sun Z. M., Sun A. Z. (1993). Trace elements and Chinese herbal medicine (Chinese). Beijing: China Traditional Chinese Medicine Press, 122–483.
    1. Choi H., Oh D., Kim M., Cai L., Lee J., Kim E., et al. (2022). Copper deficiency affects the developmental competence of porcine oocytes matured in vitro . Front. Cell Dev. Biol. 10, 993030. 10.3389/fcell.2022.993030 - DOI - PMC - PubMed
    1. Czlonkowska A., Litwin T., Dusek P., Ferenci P., Lutsenko S., Medici V., et al. (2018). Wilson disease. Nat. Rev. Dis. Prim. 4, 21. 10.1038/s41572-018-0018-3 - DOI - PMC - PubMed

LinkOut - more resources