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Review
. 2022 Mar;2(1):100021.
doi: 10.1016/j.ccmp.2022.100021. Epub 2022 Feb 5.

Herbal Remedies, Nutraceuticals, and Dietary Supplements for COVID-19 Management: An Update

Vivek P Chavda  1   2 , Aayushi B Patel  3 , Disha Vihol  3 , Darsh D Vaghasiya  3 , Khandu Muhammed Saad Bashir Ahmed  3 , Kushal U Trivedi  3 , Divyang J Dave  2
Affiliations
Review

Herbal Remedies, Nutraceuticals, and Dietary Supplements for COVID-19 Management: An Update

Vivek P Chavda et al. Clin Complement Med Pharmacol. 2022 Mar.

Abstract

Currently, the world is facing a Coronavirus pandemic with a grave deficiency of specific therapy for Coronavirus Disease (COVID-19). Moreover, scientists attempt to discover the most refined approach to prevent this condition. Regarding COVID-19 infection, herbal medicines with immunomodulatory effects may offer patients a promising preventive treatment option. Several ayurvedic and Traditional Chinese Medicine (TCM) are effective during this worrisome Coronavirus pandemic i.e. Tinospora cordifolia (Willd.) Miers, Withania somnifera (L.) Dunal, Scutellaria baicalensis Georgi, Curcuma longa L. etc. TCM was shown to be utilized with over 90% efficacy when the COVID-19 pandemic broke out in early 2020. In addition to herbal treatments and nutraceutical drugs, dietary supplements such as vitamins and amino acid derivatives also play a significant part in COVID-19 management. Diet can assist in regulating inflammation, while nutraceuticals can aid in the prevention of viral invasion. Functional amino acids (e.g., arginine, cysteine, glutamate, glutamine, glycine, taurine, and tryptophan) and glutathione, which are all abundant in animal-sourced foodstuffs, are crucial for optimum immunity and health in humans and animals. The goal of this article is to thoroughly evaluate recent statistics on the effectiveness of herbal medicines in COVID-19, the antiviral activity of nutraceuticals, and the significance of these results in creating dietary supplements that would enhance innate immunity and contribute as preventive measures against severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2).

Keywords: Ayurvedic remedies; COVID-19 management; Chinese herbs; Dietary supplements; Herbal drugs; Nutraceutical drugs; Traditional Chinese Medicine.

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Figures

Image, graphical abstract
Graphical abstract
Fig 1
Fig. 1
Immunopathophysiology of COVID-19 (Adopted from (Eijk et al., 2021) under creative commons CC-BY-NC—ND).
Fig 2
Fig. 2
Chalcones isolated from Angelica keiskei with Anti-SARS CoV activity targeting PLpro.
Fig 3
Fig. 3
Data base search methodology with inclusion/exclusion criteria.
See this image and copyright information in PMC

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