Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices

Periklis Charalampous¹, Juanita A Haagsma¹, Lea S Jakobsen², Vanessa Gorasso^{3

4}, Isabel Noguer⁵, Alicia Padron-Monedero⁵, Rodrigo Sarmiento^{5

6}, João Vasco Santos^{7

8

9}, Scott A McDonald¹⁰, Dietrich Plass¹¹, Grant M A Wyper¹², Ricardo Assunção¹³, Elena von der Lippe¹⁴, Balázs Ádám¹⁵, Ala'a AlKerwi¹⁶, Jalal Arabloo¹⁷, Ana Lúcia Baltazar¹⁸, Boris Bikbov¹⁹, Maria Borrell-Pages²⁰, Iris Brus¹, Genc Burazeri²¹, Serafeim C Chaintoutis²², José Chen-Xu^{23

24}, Nino Chkhaberidze²⁵, Seila Cilovic-Lagarija²⁶, Barbara Corso²⁷, Sarah Cuschieri²⁸, Carlotta Di Bari⁴, Keren Dopelt^{29

30}, Mary Economou³¹, Theophilus I Emeto^{32

33

34}, Peter Fantke³⁵, Florian Fischer³⁶, Alberto Freitas^{7

8}, Juan Manuel García-González³⁷, Federica Gazzelloni³⁸, Mika Gissler^{39

40

41

42}, Artemis Gkitakou⁴³, Hakan Gulmez⁴⁴, Sezgin Gunes^{45

46}, Sebastian Haller⁴⁷, Romana Haneef⁴⁸, Cesar A Hincapié^{49

50

51}, Paul Hynds⁵², Jane Idavain⁵³, Milena Ilic⁵⁴, Irena Ilic⁵⁵, Gaetano Isola⁵⁶, Zubair Kabir⁵⁷, Maria Kamusheva⁵⁸, Pavel Kolkhir^{59

60}, Naime Meriç Konar⁶¹, Polychronis Kostoulas⁶², Mukhtar Kulimbet^{63

64}, Carlo La Vecchia⁶⁵, Paolo Lauriola⁶⁶, Miriam Levi⁶⁷, Marjeta Majer⁶⁸, Enkeleint A Mechili^{69

70}, Lorenzo Monasta⁷¹, Stefania Mondello⁷², Javier Muñoz Laguna^{49

50

51}, Evangelia Nena⁷³, Edmond S W Ng⁷⁴, Paul Nguewa⁷⁵, Vikram Niranjan⁷⁶, Iskra Alexandra Nola⁶⁸, Rónán O'Caoimh^{77

78}, Marija Obradović⁷⁹, Elena Pallari⁸⁰, Mariana Peyroteo⁸¹, Vera Pinheiro^{82

83}, Nurka Pranjic⁸⁴, Miguel Reina Ortiz⁸⁵, Silvia Riva⁸⁶, Cornelia Melinda Adi Santoso⁸⁷, Milena Santric Milicevic⁸⁸, Tugce Schmitt⁸⁹, Niko Speybroeck⁹⁰, Maximilian Sprügel⁹¹, Paschalis Steiropoulos⁹², Aleksandar Stevanovic⁸⁸, Lau Caspar Thygesen⁹³, Fimka Tozija⁹⁴, Brigid Unim⁹⁵, Hilal Bektaş Uysal⁹⁶, Orsolya Varga⁹⁷, Milena Vasic^{98

99}, Rafael José Vieira^{7

8}, Vahit Yigit¹⁰⁰, Brecht Devleesschauwer^{4

101}, Sara M Pires²

Affiliations

¹ Department of Public Health, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
² National Food Institute, Technical University of Denmark, Lyngby, Denmark.
³ Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.
⁴ Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
⁵ National School of Public Health, Carlos III Institute of Health, Madrid, Spain.
⁶ Medicine School, University of Applied and Environmental Sciences, Bogota, Colombia.
⁷ CINTESIS@RISE - Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine of the University of Porto, Porto, Portugal.
⁸ MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
⁹ Public Health Unit, Agrupamentos de Centro de Saúde Grande Porto V - Porto Ocidental, Administração Regional de Saúde do Norte, Porto, Portugal.
¹⁰ Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
¹¹ Department for Exposure Assessment and Environmental Health Indicators, German Environment Agency, Berlin, Germany.
¹² School of Health & Wellbeing, University of Glasgow, Glasgow, UK.
¹³ Food and Nutrition Department, National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal.
¹⁴ Department of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
¹⁵ Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
¹⁶ Directorate of Health, Service Epidemiology and Statistics, Luxembourg, Luxembourg.
¹⁷ Health Management and Economics Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran.
¹⁸ Scientific-Pedagogical Unit of Dietetics and Nutrition, Coimbra Health School, Polytechnic Institute of Coimbra, Coimbra, Portugal.
¹⁹ Dipartimento di Politiche per la Salute, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
²⁰ Cardiovascular Program ICCC, Institut d'Investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
²¹ Department of Public Health, Faculty of Medicine, University of Medicine, Tirana, Albania.
²² Diagnostic Laboratory, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
²³ NOVA National School of Public Health, Public Health Research Centre, Universidade NOVA de Lisboa, Lisbon, Portugal.
²⁴ Public Health Unit, Primary Health Care Cluster Baixo Mondego, Coimbra, Portugal.
²⁵ Department of Medical Statistics, National Center for Disease Control and Public Health of Georgia, Georgia, Georgia.
²⁶ Institute for Public Health FB&H, Sarajevo, Bosnia and Herzegovina.
²⁷ Neuroscience Institute, National Research Council, Padova, Italy.
²⁸ Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.
²⁹ Department of Public Health, Ashkelon Academic College, Ashkelon, Israel.
³⁰ Department of Health Policy and Management, School of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
³¹ Department of Nursing, School of Health Sciences, Cyprus University of Technology, Limassol, Cyprus.
³² Public Health & Tropical Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia.
³³ World Health Organization Collaborating Center for Vector-Borne and Neglected Tropical Diseases, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia.
³⁴ Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, Australia.
³⁵ Quantitative Sustainability Assessment, Department of Environmental and Resource Engineering, Technical University of Denmark, Lyngby, Denmark.
³⁶ Institute of Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
³⁷ Department of Sociology, Universidad Pablo de Olavide, Seville, Spain.
³⁸ Institute and Faculty of Actuaries, London, UK.
³⁹ Department of Knowledge Brokers, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
⁴⁰ Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
⁴¹ Academic Primary Health Care Centre, Stockholm, Sweden.
⁴² Research Centre for Child Psychiatry and Invest Research Flagship, University of Turku, Turku, Finland.
⁴³ Department of Internal Medicine and Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
⁴⁴ Department of Family Medicine, Faculty of Medicine, İzmir Democracy University, Izmir, Turkey.
⁴⁵ Department of Multidisciplinary Molecular Medicine, Graduate Institute, Ondokuz Mayis University, Samsun, Turkey.
⁴⁶ Department of Medical Biology, Medical Faculty, Ondokuz Mayis University, Samsun, Turkey.
⁴⁷ Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
⁴⁸ Department of Non-Communicable Diseases and Injuries, Santé Publique France, Saint-Maurice, France.
⁴⁹ EBPI-UZWH Musculoskeletal Epidemiology Research Group, University of Zurich and Balgrist University Hospital, Zurich, Switzerland.
⁵⁰ Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich, Zurich, Switzerland.
⁵¹ University Spine Centre Zurich (UWZH), Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
⁵² Environmental Sustainability and Health Institute, Technological University Dublin, Dublin, Ireland.
⁵³ Department of Health Statistics, National Institute for Health Development, Tallinn, Estonia.
⁵⁴ Department of Epidemiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
⁵⁵ Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
⁵⁶ Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania, Italy.
⁵⁷ Public Health & Epidemiology, School of Public Health, University College Cork, Cork, Ireland.
⁵⁸ Department of Organization & Economics of Pharmacy, Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
⁵⁹ Institute of Allergology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, and Humboldt-Universität zu Berlin, Berlin, Germany.
⁶⁰ Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
⁶¹ Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kirsehir Ahi Evran University, Kirsehir, Turkey.
⁶² Laboratory of Epidemiology and Artificial Intelligence, Faculty of Public Health, University of Thessaly, Thessaly, Greece.
⁶³ Health Research Institute, Al Farabi Kazakh National University, Almaty, Kazakhstan.
⁶⁴ Atchabarov Scientific Research Institute of Fundamental Medicine, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
⁶⁵ Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
⁶⁶ Italian Network of Sentinel Physicians for the Environment (RIMSA), International Society Doctors for the Environment (ISDE), Federazione Nazione Ordine dei Medici (FNOMCeO), Arezzo, Italy.
⁶⁷ Epidemiology Unit, Department of Prevention, Local Health Authority Tuscany Centre, Florence, Italy.
⁶⁸ Andrija Štampar School of Public Health, School of Medicine, University of Zagreb, Zagreb, Croatia.
⁶⁹ Clinic of Social and Family Medicine, School of Medicine, University of Crete, Crete, Greece.
⁷⁰ Department of Healthcare, Faculty of Public Health, University of Vlora, Vlora, Albania.
⁷¹ Institute of Maternal, Child Health - IRCCS Burlo Garofolo, Trieste, Italy.
⁷² Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.
⁷³ Laboratory of Social Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
⁷⁴ Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
⁷⁵ Department of Microbiology and Parasitology, ISTUN Institute of Tropical Health, IdiSNA (Navarra Institute for Health Research), University of Navarra, Pamplona, Spain.
⁷⁶ School of Public Health, Physiotherapy and Sport Sciences, University College Dublin, Dublin, Ireland.
⁷⁷ Department of Geriatric Medicine, Mercy University Hospital, Grenville Place, Cork City, Ireland.
⁷⁸ Department of Gerontology and Rehabilitation, University College Cork, St Finbarr's Hospital, Douglas road, Cork City, Ireland.
⁷⁹ Department of Preventive and Pediatric Dentistry, Faculty of Medicine, University of Banja Luka, Bosnia, Herzegovina.
⁸⁰ Health Innovation Network, Minerva House, Montague Cl, London, UK.
⁸¹ Comprehensive Health Research Centre, NOVA Medical School, Universidade NOVA de Lisboa, Lisboa, Portugal.
⁸² Public Health Unit, Matosinhos Local Health Unit, Matosinhos, Portugal.
⁸³ CINTESIS - Centre for Health Technology and Services Research, Faculty of Medicine of the University of Porto, Porto, Portugal.
⁸⁴ Department of Occupational Medicine, School of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina.
⁸⁵ School of Public and Population Health, Boise State University, Boise, USA.
⁸⁶ Department of Psychology and Pedagogic Science, St Mary's University, London, UK.
⁸⁷ Faculty of Public Health, University of Debrecen, Debrecen, Hungary.
⁸⁸ Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
⁸⁹ Department of International Health, Care and Public Health Research Institute - CAPHRI, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
⁹⁰ Institute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium.
⁹¹ Department of Neurology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
⁹² Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
⁹³ National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
⁹⁴ Faculty of Medicine, Saints Cyril and Methodius University of Skopje, Skopje, North Macedonia.
⁹⁵ Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore Di Sanità, Rome, Italy.
⁹⁶ Department of Internal Medicine, Adnan Menderes University School of Medicine, Aydin, Turkey.
⁹⁷ Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
⁹⁸ Faculty of Dentistry Pancevo, University Business Academy in Novi Sad, Pancevo, Serbia.
⁹⁹ Institute of Public Health of Serbia Dr Milan Jovanović Batut, Belgrade, Serbia.
¹⁰⁰ Department of Health Management, Suleyman Demirel University, Isparta, Turkey.
¹⁰¹ Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium.

PMID: 36621004
PMCID: PMC9990389
DOI: 10.1017/S0950268823000031

Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices

Periklis Charalampous et al. Epidemiol Infect. 2023.

. 2023 Jan 9:151:e19.

doi: 10.1017/S0950268823000031.

Authors

Affiliations

¹ Department of Public Health, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
² National Food Institute, Technical University of Denmark, Lyngby, Denmark.
³ Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.
⁴ Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
⁵ National School of Public Health, Carlos III Institute of Health, Madrid, Spain.
⁶ Medicine School, University of Applied and Environmental Sciences, Bogota, Colombia.
⁷ CINTESIS@RISE - Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine of the University of Porto, Porto, Portugal.
⁸ MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
⁹ Public Health Unit, Agrupamentos de Centro de Saúde Grande Porto V - Porto Ocidental, Administração Regional de Saúde do Norte, Porto, Portugal.
¹⁰ Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
¹¹ Department for Exposure Assessment and Environmental Health Indicators, German Environment Agency, Berlin, Germany.
¹² School of Health & Wellbeing, University of Glasgow, Glasgow, UK.
¹³ Food and Nutrition Department, National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal.
¹⁴ Department of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
¹⁵ Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
¹⁶ Directorate of Health, Service Epidemiology and Statistics, Luxembourg, Luxembourg.
¹⁷ Health Management and Economics Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran.
¹⁸ Scientific-Pedagogical Unit of Dietetics and Nutrition, Coimbra Health School, Polytechnic Institute of Coimbra, Coimbra, Portugal.
¹⁹ Dipartimento di Politiche per la Salute, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
²⁰ Cardiovascular Program ICCC, Institut d'Investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
²¹ Department of Public Health, Faculty of Medicine, University of Medicine, Tirana, Albania.
²² Diagnostic Laboratory, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
²³ NOVA National School of Public Health, Public Health Research Centre, Universidade NOVA de Lisboa, Lisbon, Portugal.
²⁴ Public Health Unit, Primary Health Care Cluster Baixo Mondego, Coimbra, Portugal.
²⁵ Department of Medical Statistics, National Center for Disease Control and Public Health of Georgia, Georgia, Georgia.
²⁶ Institute for Public Health FB&H, Sarajevo, Bosnia and Herzegovina.
²⁷ Neuroscience Institute, National Research Council, Padova, Italy.
²⁸ Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.
²⁹ Department of Public Health, Ashkelon Academic College, Ashkelon, Israel.
³⁰ Department of Health Policy and Management, School of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
³¹ Department of Nursing, School of Health Sciences, Cyprus University of Technology, Limassol, Cyprus.
³² Public Health & Tropical Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia.
³³ World Health Organization Collaborating Center for Vector-Borne and Neglected Tropical Diseases, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia.
³⁴ Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, Australia.
³⁵ Quantitative Sustainability Assessment, Department of Environmental and Resource Engineering, Technical University of Denmark, Lyngby, Denmark.
³⁶ Institute of Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
³⁷ Department of Sociology, Universidad Pablo de Olavide, Seville, Spain.
³⁸ Institute and Faculty of Actuaries, London, UK.
³⁹ Department of Knowledge Brokers, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
⁴⁰ Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
⁴¹ Academic Primary Health Care Centre, Stockholm, Sweden.
⁴² Research Centre for Child Psychiatry and Invest Research Flagship, University of Turku, Turku, Finland.
⁴³ Department of Internal Medicine and Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
⁴⁴ Department of Family Medicine, Faculty of Medicine, İzmir Democracy University, Izmir, Turkey.
⁴⁵ Department of Multidisciplinary Molecular Medicine, Graduate Institute, Ondokuz Mayis University, Samsun, Turkey.
⁴⁶ Department of Medical Biology, Medical Faculty, Ondokuz Mayis University, Samsun, Turkey.
⁴⁷ Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
⁴⁸ Department of Non-Communicable Diseases and Injuries, Santé Publique France, Saint-Maurice, France.
⁴⁹ EBPI-UZWH Musculoskeletal Epidemiology Research Group, University of Zurich and Balgrist University Hospital, Zurich, Switzerland.
⁵⁰ Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich, Zurich, Switzerland.
⁵¹ University Spine Centre Zurich (UWZH), Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
⁵² Environmental Sustainability and Health Institute, Technological University Dublin, Dublin, Ireland.
⁵³ Department of Health Statistics, National Institute for Health Development, Tallinn, Estonia.
⁵⁴ Department of Epidemiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
⁵⁵ Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
⁵⁶ Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania, Italy.
⁵⁷ Public Health & Epidemiology, School of Public Health, University College Cork, Cork, Ireland.
⁵⁸ Department of Organization & Economics of Pharmacy, Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
⁵⁹ Institute of Allergology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, and Humboldt-Universität zu Berlin, Berlin, Germany.
⁶⁰ Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
⁶¹ Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kirsehir Ahi Evran University, Kirsehir, Turkey.
⁶² Laboratory of Epidemiology and Artificial Intelligence, Faculty of Public Health, University of Thessaly, Thessaly, Greece.
⁶³ Health Research Institute, Al Farabi Kazakh National University, Almaty, Kazakhstan.
⁶⁴ Atchabarov Scientific Research Institute of Fundamental Medicine, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
⁶⁵ Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
⁶⁶ Italian Network of Sentinel Physicians for the Environment (RIMSA), International Society Doctors for the Environment (ISDE), Federazione Nazione Ordine dei Medici (FNOMCeO), Arezzo, Italy.
⁶⁷ Epidemiology Unit, Department of Prevention, Local Health Authority Tuscany Centre, Florence, Italy.
⁶⁸ Andrija Štampar School of Public Health, School of Medicine, University of Zagreb, Zagreb, Croatia.
⁶⁹ Clinic of Social and Family Medicine, School of Medicine, University of Crete, Crete, Greece.
⁷⁰ Department of Healthcare, Faculty of Public Health, University of Vlora, Vlora, Albania.
⁷¹ Institute of Maternal, Child Health - IRCCS Burlo Garofolo, Trieste, Italy.
⁷² Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.
⁷³ Laboratory of Social Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
⁷⁴ Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
⁷⁵ Department of Microbiology and Parasitology, ISTUN Institute of Tropical Health, IdiSNA (Navarra Institute for Health Research), University of Navarra, Pamplona, Spain.
⁷⁶ School of Public Health, Physiotherapy and Sport Sciences, University College Dublin, Dublin, Ireland.
⁷⁷ Department of Geriatric Medicine, Mercy University Hospital, Grenville Place, Cork City, Ireland.
⁷⁸ Department of Gerontology and Rehabilitation, University College Cork, St Finbarr's Hospital, Douglas road, Cork City, Ireland.
⁷⁹ Department of Preventive and Pediatric Dentistry, Faculty of Medicine, University of Banja Luka, Bosnia, Herzegovina.
⁸⁰ Health Innovation Network, Minerva House, Montague Cl, London, UK.
⁸¹ Comprehensive Health Research Centre, NOVA Medical School, Universidade NOVA de Lisboa, Lisboa, Portugal.
⁸² Public Health Unit, Matosinhos Local Health Unit, Matosinhos, Portugal.
⁸³ CINTESIS - Centre for Health Technology and Services Research, Faculty of Medicine of the University of Porto, Porto, Portugal.
⁸⁴ Department of Occupational Medicine, School of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina.
⁸⁵ School of Public and Population Health, Boise State University, Boise, USA.
⁸⁶ Department of Psychology and Pedagogic Science, St Mary's University, London, UK.
⁸⁷ Faculty of Public Health, University of Debrecen, Debrecen, Hungary.
⁸⁸ Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
⁸⁹ Department of International Health, Care and Public Health Research Institute - CAPHRI, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
⁹⁰ Institute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium.
⁹¹ Department of Neurology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
⁹² Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
⁹³ National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
⁹⁴ Faculty of Medicine, Saints Cyril and Methodius University of Skopje, Skopje, North Macedonia.
⁹⁵ Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore Di Sanità, Rome, Italy.
⁹⁶ Department of Internal Medicine, Adnan Menderes University School of Medicine, Aydin, Turkey.
⁹⁷ Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
⁹⁸ Faculty of Dentistry Pancevo, University Business Academy in Novi Sad, Pancevo, Serbia.
⁹⁹ Institute of Public Health of Serbia Dr Milan Jovanović Batut, Belgrade, Serbia.
¹⁰⁰ Department of Health Management, Suleyman Demirel University, Isparta, Turkey.
¹⁰¹ Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium.

PMID: 36621004
PMCID: PMC9990389
DOI: 10.1017/S0950268823000031

Abstract

This systematic literature review aimed to provide an overview of the characteristics and methods used in studies applying the disability-adjusted life years (DALY) concept for infectious diseases within European Union (EU)/European Economic Area (EEA)/European Free Trade Association (EFTA) countries and the United Kingdom. Electronic databases and grey literature were searched for articles reporting the assessment of DALY and its components. We considered studies in which researchers performed DALY calculations using primary epidemiological data input sources. We screened 3053 studies of which 2948 were excluded and 105 studies met our inclusion criteria. Of these studies, 22 were multi-country and 83 were single-country studies, of which 46 were from the Netherlands. Food- and water-borne diseases were the most frequently studied infectious diseases. Between 2015 and 2022, the number of burden of infectious disease studies was 1.6 times higher compared to that published between 2000 and 2014. Almost all studies (97%) estimated DALYs based on the incidence- and pathogen-based approach and without social weighting functions; however, there was less methodological consensus with regards to the disability weights and life tables that were applied. The number of burden of infectious disease studies undertaken across Europe has increased over time. Development and use of guidelines will promote performing burden of infectious disease studies and facilitate comparability of the results.

Keywords: Burden of disease; disability-adjusted life years; infectious diseases; methodology; systematic review.

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Figures

**Fig. 1.**
Flowchart of the literature search and study selection.

**Fig. 2.**
Number of single-country and multi-country independent burden of infectious disease studies per year of publication, geographic coverage and infectious cause category studied.

**Fig. 3.**
Methodological approaches used to estimate YLL and YLD in independent burden of infectious disease studies, 2000–2022*. *Proportions for burden of infectious disease studies that included years of life lost calculations were reported for 102 out of 105 studies, while for those included years lived with disability were reported for 95 out of 105 studies.

See this image and copyright information in PMC

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Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices

Affiliations

Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices

Authors

Affiliations

Abstract

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References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical

Miscellaneous