A Tedious Journey: Cardiomyocyte Proliferation Requires More Than S-Phase Entry and Loss of Polyploidization

Dong Ding¹, Thomas Braun^{1

2

3}

Affiliations

¹ Department of Cardiac Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany (D.D., T.B.).
² German Center for Cardiovascular Research (DZHK), Rhine Main, Germany (T.B.).
³ German Center for Lung Research (DZL), Giessen, Germany (T.B.).

Editorial

Dong Ding et al. Circulation. 2023.

. 2023 Jan 10;147(2):154-157.

doi: 10.1161/CIRCULATIONAHA.122.062784. Epub 2023 Jan 9.

Dong Ding¹, Thomas Braun^{1

2

3}

¹ Department of Cardiac Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany (D.D., T.B.).
² German Center for Cardiovascular Research (DZHK), Rhine Main, Germany (T.B.).
³ German Center for Lung Research (DZL), Giessen, Germany (T.B.).

No abstract available

Keywords: Editorials; S phase; cardiomyocyte proliferation; cytokinesis; heart regeneration; polyploid.

Comment on

Cardiac Troponin I-Interacting Kinase Affects Cardiomyocyte S-Phase Activity but Not Cardiomyocyte Proliferation.
Reuter SP, Soonpaa MH, Field D, Simpson E, Rubart-von der Lohe M, Lee HK, Sridhar A, Ware SM, Green N, Li X, Ofner S, Marchuk DA, Wollert KC, Field LJ. Reuter SP, et al. Circulation. 2023 Jan 10;147(2):142-153. doi: 10.1161/CIRCULATIONAHA.122.061130. Epub 2022 Nov 16. Circulation. 2023. PMID: 36382596 Free PMC article.
Increasing Mononuclear Diploid Cardiomyocytes by Loss of E2F Transcription Factor 7/8 Fails to Improve Cardiac Regeneration After Infarct.
Yu Z, Zhang L, Cattaneo P, Guimarães-Camboa N, Fang X, Gu Y, Peterson KL, Bogomolovas J, Cuitino C, Leone GW, Chen J, Evans SM. Yu Z, et al. Circulation. 2023 Jan 10;147(2):183-186. doi: 10.1161/CIRCULATIONAHA.122.061018. Epub 2023 Jan 9. Circulation. 2023. PMID: 36622904 Free PMC article. No abstract available.