Genotype by sex interactions in ankylosing spondylitis

Zhixiu Li^{1

2}, Allan F McRae³, Geng Wang^{3

4}, Jonathan J Ellis^{1

2}, Jessica Whyte^{1

2}, Tony J Kenna^{2

5}, Matthew A Brown^{6

7}, David M Evans^{8

9

10}

Affiliations

¹ Centre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.
² Queensland University of Technology, Faculty of Health, School of Biomedical Sciences, Brisbane, Queensland, Australia.
³ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
⁴ University of Queensland Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.
⁵ Centre for Immunology and Infection Control, Queensland University of Technology, Brisbane, Queensland, Australia.
⁶ Department of Medical and Molecular Genetics, Faculty of Life Sciences and Medicine, King's College London, London, UK.
⁷ Genomics England, London, UK.
⁸ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. d.evans1@uq.edu.au.
⁹ University of Queensland Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia. d.evans1@uq.edu.au.
¹⁰ Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK. d.evans1@uq.edu.au.

PMID: 36624341
DOI: 10.1038/s41588-022-01250-5

Comment

Genotype by sex interactions in ankylosing spondylitis

Zhixiu Li et al. Nat Genet. 2023 Jan.

. 2023 Jan;55(1):14-16.

doi: 10.1038/s41588-022-01250-5. Epub 2023 Jan 9.

Authors

Zhixiu Li^{1

2}, Allan F McRae³, Geng Wang^{3

4}, Jonathan J Ellis^{1

2}, Jessica Whyte^{1

2}, Tony J Kenna^{2

5}, Matthew A Brown^{6

7}, David M Evans^{8

9

10}

Affiliations

¹ Centre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.
² Queensland University of Technology, Faculty of Health, School of Biomedical Sciences, Brisbane, Queensland, Australia.
³ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
⁴ University of Queensland Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.
⁵ Centre for Immunology and Infection Control, Queensland University of Technology, Brisbane, Queensland, Australia.
⁶ Department of Medical and Molecular Genetics, Faculty of Life Sciences and Medicine, King's College London, London, UK.
⁷ Genomics England, London, UK.
⁸ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. d.evans1@uq.edu.au.
⁹ University of Queensland Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia. d.evans1@uq.edu.au.
¹⁰ Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK. d.evans1@uq.edu.au.

PMID: 36624341
DOI: 10.1038/s41588-022-01250-5

No abstract available

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Comment in

Reply to: Genotype by sex interactions in ankylosing spondylitis.
Bernabeu E, Rawlik K, Canela-Xandri O, Talenti A, Prendergast J, Tenesa A. Bernabeu E, et al. Nat Genet. 2023 Jan;55(1):17-18. doi: 10.1038/s41588-022-01251-4. Epub 2023 Jan 9. Nat Genet. 2023. PMID: 36624342 No abstract available.

Comment on

Sex differences in genetic architecture in the UK Biobank.
Bernabeu E, Canela-Xandri O, Rawlik K, Talenti A, Prendergast J, Tenesa A. Bernabeu E, et al. Nat Genet. 2021 Sep;53(9):1283-1289. doi: 10.1038/s41588-021-00912-0. Epub 2021 Sep 7. Nat Genet. 2021. PMID: 34493869

References

1. Bernabeu, E. et al. Sex differences in genetic architecture in the UK Biobank. Nat. Genet. 53, 1283–1289 (2021). - DOI
1. Bernabeu, A. et al. Reply to: Genotype by sex interactions in ankylosing spondylitis. Nat. Genet. (2022).
1. Schlosstein, L., Terasaki, P. I., Bluestone, R. & Pearson, C. M. High association of an HL-A antigen, W27, with ankylosing spondylitis. N. Engl. J. Med. 288, 704–706 (1973). - DOI
1. Zhou, X. et al. MICA, a gene contributing strong susceptibility to ankylosing spondylitis. Ann. Rheum. Dis. 73, 1552–1557 (2014). - DOI
1. Hammer, R. E., Maika, S. D., Richardson, J. A., Tang, J. P. & Taurog, J. D. Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human á2m: an animal model of HLA-B27-associated human disorders. Cell 63, 1099–1112 (1990). - DOI

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Genotype by sex interactions in ankylosing spondylitis

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Genotype by sex interactions in ankylosing spondylitis

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