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Comment
. 2023 Feb;7(2):92-93.
doi: 10.1038/s41551-022-00983-2.

A biomaterial infused into the bloodstream repairs inflamed tissue

No authors listed
Comment

A biomaterial infused into the bloodstream repairs inflamed tissue

No authors listed. Nat Biomed Eng. 2023 Feb.
No abstract available

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Comment on

  • Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues.
    Spang MT, Middleton R, Diaz M, Hunter J, Mesfin J, Banka A, Sullivan H, Wang R, Lazerson TS, Bhatia S, Corbitt J, D'Elia G, Sandoval-Gomez G, Kandell R, Vratsanos MA, Gnanasekaran K, Kato T, Igata S, Luo C, Osborn KG, Gianneschi NC, Eniola-Adefeso O, Cabrales P, Kwon EJ, Contijoch F, Reeves RR, DeMaria AN, Christman KL. Spang MT, et al. Nat Biomed Eng. 2023 Feb;7(2):94-109. doi: 10.1038/s41551-022-00964-5. Epub 2022 Dec 29. Nat Biomed Eng. 2023. PMID: 36581694 Free PMC article.

References

    1. Christman, K. L. Biomaterials for tissue repair. Science 363, 340–341 (2019). A perspective that discusses the use of acellular biomaterials for tissue repair and regeneration. - DOI - PubMed - PMC
    1. Serpooshan, V. & Wu, S. M. (eds) in Cardiovascular Regenerative Medicine: Tissue Engineering and Clinical Applications Ch. 10 (Springer, 2019). A book chapter that presents various injectable biomaterials for treating MI.
    1. Singelyn, J. M. et al. Catheter-deliverable hydrogel derived from decellularized ventricular extracellular matrix increases endogenous cardiomyocytes and preserves cardiac function post-myocardial infarction. J. Am. Coll. Cardiol. 59, 751–763 (2012). An initial study showing the efficacy of an ECM hydrogel in a rat MI model. - DOI - PubMed - PMC
    1. Seif-Naraghi, S. B. et al. Safety and efficacy of an injectable extracellular matrix hydrogel for treating myocardial infarction. Sci. Transl Med. 5, 173ra25 (2013). A study showing the efficacy of an ECM hydrogel in a porcine MI model. - DOI - PubMed
    1. Traverse, J. H. et al. First-in-man study of a cardiac extracellular matrix hydrogel in early and late myocardial infarction patients. JACC Basic Transl Sci. 4, 659–669 (2019). The first study testing an ECM hydrogel in patients. - DOI - PubMed - PMC

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