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Review
. 2023 Jan 2;185(1):V08220479.

Amyloidosis is a disease with many faces

[Article in Danish]
Magne Bl Spanggaard  1   2 , Charlotte T Hansen  1   2 , Michael Maiborg  1   3 , Aleksandra M Rojek  1   4 , Sys Vestergaard  1   5 , Hans Christian Beck  1   6 , Hanne Eh Møller  1   4 , Niels Abildgaard  1   2
Affiliations
  • PMID: 36629291
Free article
Review

Amyloidosis is a disease with many faces

[Article in Danish]
Magne Bl Spanggaard et al. Ugeskr Laeger. .
Free article

Abstract

Amyloidosis is a severe disease caused by protein misfolding and deposition in tissues and organs. Thirty-eight different proteins are known to be amyloidogenic. Amyloidosis is categorized into inherited or acquired, and systemic or localized. Light-chain (AL)- and transthyretin (ATTR) amyloidosis are the two most common subtypes. Awareness, early diagnosis, accurate subtyping and relevant treatment are crucial for the management. Novel therapies of systemic AL and ATTR amyloidosis have considerably improved outcome and survival. The aim of this review is to increase awareness and knowledge on diagnosing amyloidosis.

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