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. 2023 Jan 26;388(4):374-376.
doi: 10.1056/NEJMc2210825. Epub 2023 Jan 11.

Influenza Vaccine in Pediatric Recipients of Hematopoietic-Cell Transplants

Jennifer E Schuster  1 , Lubna Hamdan  2 , Daniel E Dulek  2 , Carrie L Kitko  2 , Einas Batarseh  2 , Zaid Haddadin  2 , Laura S Stewart  2 , Anna Stahl  2 , Molly Potter  2 , Herdi Rahman  2 , Spyros A Kalams  2 , Susan Coffin  3 , Monica I Ardura  4 , Rachel L Wattier  5 , Gabriela Maron  6 , Claire E Bocchini  7 , Elizabeth A Moulton  7 , Michael Grimley  8 , Grant Paulsen  8 , Christopher J Harrison  1 , Jason Freedman  3 , Paul A Carpenter  9 , Janet A Englund  9 , Flor M Munoz  7 , Lara Danziger-Isakov  8 , Andrew J Spieker  10 , Natasha Halasa  10 ; Pediatric HCT Flu Study Group
Collaborators, Affiliations

Influenza Vaccine in Pediatric Recipients of Hematopoietic-Cell Transplants

Jennifer E Schuster et al. N Engl J Med. .
No abstract available

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Figures

Figure 1.
Figure 1.. Hemagglutination-Inhibition Titers to Influenza Antigens.
Depicted are the raw data along with group- and time-specific estimates of the geometric mean titers for hemagglutination inhibition (HAI) along with 95% confidence intervals (indicated by I bars). P values are for the adjusted geometric mean ratios comparing high-dose trivalent influenza vaccine (HD-TIV) with standard-dose quadrivalent influenza vaccine (SD-QIV). B/Yamagata is not included in HD-TIV.
See this image and copyright information in PMC

References

    1. Ryan AL, Wadia UD, Jacoby P, et al. Immunogenicity of the inactivated influenza vaccine in children who have undergone allogeneic haematopoietic stem cell transplant. Bone Marrow Transplant 2020;55:773–9. - PMC - PubMed
    1. McManus M, Frangoul H, McCullers JA, Wang L, O’Shea A, Halasa N. Safety of high dose trivalent inactivated influenza vaccine in pediatric patients with acute lymphoblastic leukemia. Pediatr Blood Cancer 2014;61:815–20. - PMC - PubMed
    1. GiaQuinta S, Michaels MG, McCullers JA, et al. Randomized, double-blind comparison of standard-dose vs. high-dose trivalent inactivated influenza vaccine in pediatric solid organ transplant patients. Pediatr Transplant 2015;19:219–28. - PubMed
    1. Halasa NB, Savani BN, Asokan I, et al. Randomized double-blind study of the safety and immunogenicity of standard-dose trivalent inactivated influenza vaccine versus high-dose trivalent inactivated influenza vaccine in adult hematopoietic stem cell transplantation patients. Biol Blood Marrow Transplant 2016;22:528–35. - PubMed

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